Hierarchical modeling of genome‐wide Short Tandem Repeat (STR) markers infers native American prehistory

This study examines a genome‐wide dataset of 678 Short Tandem Repeat loci characterized in 444 individuals representing 29 Native American populations as well as the Tundra Netsi and Yakut populations from Siberia. Using these data, the study tests four current hypotheses regarding the hierarchical distribution of neutral genetic variation in native South American populations: (1) the western region of South America harbors more variation than the eastern region of South America, (2) Central American and western South American populations cluster exclusively, (3) populations speaking the Chibchan‐Paezan and Equatorial‐Tucanoan language stock emerge as a group within an otherwise South American clade, (4) Chibchan‐Paezan populations in Central America emerge together at the tips of the Chibchan‐Paezan cluster. This study finds that hierarchical models with the best fit place Central American populations, and populations speaking the Chibchan‐Paezan language stock, at a basal position or separated from the South American group, which is more consistent with a serial founder effect into South America than that previously described. Western (Andean) South America is found to harbor similar levels of variation as eastern (Equatorial‐Tucanoan and Ge‐Pano‐Carib) South America, which is inconsistent with an initial west coast migration into South America. Moreover, in all relevant models, the estimates of genetic diversity within geographic regions suggest a major bottleneck or founder effect occurring within the North American subcontinent, before the peopling of Central and South America. Am J Phys Anthropol 2010. © 2009 Wiley‐Liss, Inc

Allele · Archaeology · Beringia · Biology · Evolutionary biology · Founder effect · Geography · Pleistocene · Prehistory · Regional variation · Archaeology and ancient environmental studies · Forensic and Genetic Research · Race, Genetics, and Society

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  Incluir item

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  Incluir item

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  Incluir item

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  Incluir item

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  Incluir item

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  Open Access•C M Stojanowski, Kent M Johnson et al.•Anthropological Perspectives on…•2013

  Incluir item

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  Open Access•Johnston Birchall, Joshua Birchall et al.•Native Languages of South America•1920

  Incluir item

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  Open Access•Sidia M Callegari‐jacque, Sidia M Callegari‐Jacques et al.•American Journal of Physical…•2011

  Incluir item

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  Open Access•Lars Fehren-Schmitz, Kelly M Harkins et al.•Quaternary International•2017

  Incluir item

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  Open Access•Maria Regueiro, Joseph Alvarez et al.•American Journal of Physical…•2013

  Incluir item

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  Open Access•Antonio F Pardiñas, A Roca et al.•American Journal of Physical…•2014

  Incluir item

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  Ryan M Ellsworth, Drew H Bailey et al.•Current Anthropology•2014

  Incluir item

• MtDNA Analysis of a Prehistoric Oneota Population

  Open Access•Anne C Stone, M Stoneking•The American Journal of Human…•1998

  Incluir item

• Genetic Structure of Human Populations

  Open Access•Noah A Rosenberg, Jonathan K Pritchard et al.•Science•2002

  Incluir item

• Clines, Clusters, and the Effect of Study Design on the Inference of Human Population Structure

  Open Access•Noah A Rosenberg, Saurabh Mahajan et al.•PLoS Genetics•2005

  Incluir item

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  Open Access•INGER SKREDE, Pernille Bronken Eidesen et al.•Molecular Ecology•2006

  Incluir item

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  Open Access•Eduardo Tarazona‐santo, Eduardo Tarazona-Santos et al.•The American Journal of Human…•2001

  Incluir item

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  Open Access•Sohini Ramachandran, Omkar Deshpande et al.•Proceedings of the National…•2005

  Incluir item

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  Open Access•Erika Tamm, Toomas Kivisild et al.•PLoS ONE•2007

  Incluir item

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  Open Access•Sijia Wang, Cecil M Lewis et al.•PLoS Genetics•2007

  Incluir item

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  Open Access•Nelson J R Fagundes, Ricardo Kanitz et al.•The American Journal of Human…•2008

  Incluir item

• Estimation of the Coancestry Coefficient

  Open Access•John Reynolds, B S Weir et al.•Genetics•1983

  Incluir item

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  Open Access•M Moraga, Mauricio L Moraga et al.•American Journal of Physical…•2000

  Incluir item

• Land, language, and loci

  Open Access•Cecil M Lewis, Raúl Y Tito et al.•American Journal of Physical…•2005

  Incluir item

• Distribution of the four founding lineage haplotypes in native Americans suggests a single wave of migration for the New World

  Open Access•D Andrew Merriwether, Francisco Rothhammer et al.•American Journal of Physical…•1995

  Incluir item

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  Open Access•Carles Lalueza-Fox, C Lalueza‐Fox et al.•American Journal of Physical…•2003

  Incluir item

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  Incluir item

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  Jeffrey C Long, Rick A Kittles•Human Biology•2009

  Incluir item

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  Open Access•Donata Luiselli, Lucia Simoni et al.•American Journal of Physical…•2000

  Incluir item