Molecular characterization of a pre‐Columbian mummy and in situ coprolite

Dados Bibliográficos

ID8320447
AutoresStefania Luciani (0000-0002-6078-4041, Università di Camerino), G Fornaciari (0000-0002-1334-1707, University of Pisa), Olga Rickards (0000-0003-2880-7466, University of Rome Tor Vergata), Cristina Martinez‐labarga (0000-0003-0439-0379, University of Rome Tor Vergata), Cristina Martínez Labarga, Franco Rollo (Università di Camerino, autor correspondente)
Ano2006
Volume129
Fascículo4
Páginas620-629
Data de publicação2006-04-01
Peer ReviewedSim
Open AccessSim
TipoARTICLE
PeriódicoAmerican Journal of Physical Anthropology (JOURNAL)
Identificadores do periódicoISSN: 0002-9483 • E-ISSN: 1096-8644
EditoraWiley (PUBLISHER • GB)
DOI10.1002/ajpa.20314
PMID16342258
OpenAlexW2056806130
IdiomaEN
Citações recebidas4
Referências citadas30

The history of Homo sapiens dispersal around the world and inherent interpopulation contacts and conflicts has given rise to several transitions in his relationships with the natural world, with the final result of changes in the patterns of infectious disease (McMichael [2001] Ecosystem Health 7:107–115 ). Of particular interest, in this context, is the contact between Amerindians and Europeans that started at the end of the 15th century, and the resulting exchange of microbes. We successfully recovered ancient DNA from a pre‐Columbian mummy from Cuzco (Peru), radiocarbon‐dated to 980–1170 AD, for which consistent mtDNA amplifications and sequences were obtained. The analysis of mtDNA revealed that the mummy's haplogroup was characteristic of Native American populations. We also investigated a sample of feces directly isolated from the intestines of the mummy, using a polymerase chain reaction system designed to detect the broadest spectrum of bacterial DNAs. The analysis of results, following a criterion of “paleoecological consistency” (Rollo and Marota [1998] Philos. Trans. R. Soc. Lond. [Biol.] 354: 111–119 ), demonstrated that some vestiges of the original microbial flora of the feces were preserved. In particular, we were able to identify the DNA of Haemophylus parainfluenzae , thus suggesting that this recently recognized pathogen was present in precontact Native Americans. Am J Phys Anthropol, 2006. © 2005 Wiley‐Liss, Inc

Ancient DNA · Archaeology · Biological dispersal · Biology · Context (archaeology) · Evolutionary biology · Feces · Gene · Geography · Haplogroup · Haplotype · Homo sapiens · Mitochondrial DNA · Population · Radiocarbon dating · Zoology · Demography · Ecology · Forensic and Genetic Research · Genetics · Paleontology · Paleopathology and ancient diseases · Yersinia bacterium, plague, ectoparasites research