Risk Factors of Metabolic Syndrome Among Patients Receiving Antipsychotics

A Retrospective Study

Dados Bibliográficos

ID8905938
AutoresSamer Hammoudeh (0000-0003-0805-8111, Weill Cornell Medical College in Qatar), Hawra Al Lawati (0000-0001-5228-1025, Weill Cornell Medical College in Qatar), Suhaila Ghuloum (0000-0002-1384-4179, Hamad Medical Corporation), Huma Iram (Hamad Medical Corporation), Arij Yehya (0000-0001-9956-3636, Weill Cornell Medical College in Qatar), Imen Becetti (0000-0002-3363-7441, Weill Cornell Medical College in Qatar), Nora AlFakhri (Weill Cornell Medical College in Qatar), Nora Al-fakhri, Hany Ghabrash (Hamad Medical Corporation), Mena Shehata (0000-0002-6358-1573, Hamad Medical Corporation), Nighat Ajmal (Hamad Medical Corporation), Iman Amro (0000-0001-7358-7963, Weill Cornell Medical College in Qatar), Hira Safdar (Hamad Medical Corporation), Yassin Eltorki (0000-0002-5110-784X, Hamad Medical Corporation), Hassen Al-Amin (0000-0001-6358-1541, Weill Cornell Medical College in Qatar, autor correspondente)
Ano2019
Volume56
Fascículo4
Páginas760-770
Data de publicação2019-12-28
Peer ReviewedSim
Open AccessSim
TipoARTICLE
PeriódicoCommunity Mental Health Journal (JOURNAL)
Identificadores do periódicoISSN: 0010-3853 • E-ISSN: 1573-2789
EditoraSpringer Science+Business Media (PUBLISHER • DE)
DOI10.1007/s10597-019-00537-y
PMID31884574
OpenAlexW2997115094
IdiomaEN
Citações recebidas1
Referências citadas47

This study aimed to assess the differential effects of first-generation (FGA) and second-generation antipsychotics (SGA) on the prevalence of risk factors for metabolic syndrome among mentally ill patients in Qatar. We also wanted to check if there is proper adherence with the guidelines for prescribing antipsychotics and the monitoring of metabolic effects in this population. We collected the available retrospective data (socio-demographic, psychiatric, anthropometric, and metabolic measures) from the records of 439 patients maintained on antipsychotics. The majority were males, married, employed, having a psychotic disorder, and receiving SGA. Patients on SGA showed more obesity, higher BP, and more elevated triglycerides compared to those on FGA. The prevalence of the abnormal metabolic measures was high in this sample, but those on SGA showed a significantly higher prevalence of abnormal body mass index and BP. Obesity and hypertension were common in patients maintained on antipsychotics, especially those on SGA. Polypharmacy was common, and many metabolic measures were not monitored properly in those maintained on antipsychotics. More prospective studies with guided monitoring of the patients' clinical status and metabolic changes are needed to serve better this population of patients

Anthropometry · Antipsychotic · Body mass index · Environmental health · Metabolic syndrome · Obesity · Polypharmacy · Population · Psychiatry · Retrospective cohort study · Schizophrenia (object-oriented programming · Cardiovascular Function and Risk Factors · Diabetes Treatment and Management · Internal Medicine · Medicine · Schizophrenia research and treatment · Pediatrics