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Behavioral and Motivational Effects of Immune-System Activation

Bibliographic Data

ID10131242
AuthorsSusan J Larson (Concordia College - Minnesota, corresponding author)
Year2002
Volume129
Issue4
Pages401-414
Publication date2002-10-01
Open AccessNo
TypeARTICLE
VenueThe Journal of General Psychology (JOURNAL)
Journal identifiersISSN: 0022-1309 • E-ISSN: 1940-0888
PublisherInforma UK Limited (PUBLISHER • GB)
DOI10.1080/00221300209602104
PMID12494991
OpenAlexW2032229380
LanguageEN
Citations received2
References cited38

Immune-system activity induces changes in animal behavior such as decreased food intake, decreased exploratory behavior, increased sleep, and impaired cognitive functioning. These changes are mediated by proinflammatory cytokines, and the administration of cytokines produces the same profile of behavior change as do infection and inflammation. Results demonstrating differential effects of immune-system activation depending on environmental contingencies and physiological states support the hypothesis that the behavioral effects of immune activity may be mediated by motivation. In this article, the author outlines the behavioral changes induced by immune-system activation and discusses evidence for a motivational analysis of immune-induced behavior change and the potential involvement of motivation in human sickness behavior

Cognition · Immune system · Inflammation · Proinflammatory cytokine · Sickness behavior · Immune Cell Function and Interaction · Immunology · Medicine · Neuroendocrine regulation and behavior · Neuroscience · Psychology · Stress Responses and Cortisol

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Citations per year0.18
Citation span2015 - 2015 (1)
Highly citedNo

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