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The Bias Dynamics Model

Correcting for Meta-biases in Therapeutic Prediction

Bibliographic Data

ID10707601
AuthorsAdrian Erasmus (0000-0001-8944-1598, University of Alabama, corresponding author)
Year2023
Volume90
Issue5
Pages1204-1213
Publication date2023-12-01
Open AccessYes
TypeARTICLE
VenuePhilosophy of Science (JOURNAL)
Journal identifiersISSN: 0031-8248 • E-ISSN: 1539-767X
PublisherCambridge University Press (CUP) (PUBLISHER)
DOI10.1017/psa.2023.66
OpenAlexW4364365443
LanguageEN
Citations received1
References cited15

Inferences from clinical research results to estimates of therapeutic effectiveness suffer due to various biases. I argue that predictions of medical effectiveness are prone to failure because current medical research overlooks the impacts of a particularly detrimental set of biases: meta-biases. Meta-biases are linked to higher-level characteristics of medical research and their effects are only observed when comparing sets of studies that share certain meta-level properties. I offer a model for correcting research results based on meta-research evidence, the bias dynamics model, which employs regularly updated empirical bias coefficients to attenuate estimates of therapeutic effectiveness

Econometrics · Economics · Meta-analysis · Publication bias · Set (abstract data type) · Computer Science · Health Systems, Economic Evaluations, Quality of Life · Medicine · Meta-analysis and systematic reviews · Statistical Methods in Clinical Trials

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Citations per year0.5
Citation span2024 - 2024 (1)
Highly citedNo

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