Gender in the allocation of organs in kidney transplants
Meta-analysis
Bibliographic Data
| ID | 10723728 |
|---|---|
| Authors | Erika Vieira Almeida e Santiago (Universidade Federal de Minas Gerais), Micheline Rosa Silveira (0000-0001-7002-4428, Universidade Federal de Minas Gerais), Vânia Eloisa De Araújo (Universidade Católica de Minas Gerais, Brazil), Katia de Paula Farah (0000-0002-8978-4512, Universidade Federal de Minas Gerais), Francisco De Assis Acurcio (0000-0002-5880-5261, Universidade Federal de Minas Gerais), Maria Das Graças B Ceccato (0000-0002-4340-0659, Universidade Federal de Minas Gerais) |
| Year | 2015 |
| Volume | 49 |
| Issue | 0 |
| Pages | 68-68 |
| Publication date | 2015-01-01 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Revista de Saúde Pública (JOURNAL) |
| Journal identifiers | ISSN: 0034-8910 • E-ISSN: 0034-8910 |
| Publisher | FapUNIFESP (SciELO) (PUBLISHER) |
| DOI | 10.1590/s0034-8910.2015049005822 |
| PMID | 26465666 |
| OpenAlex | W2233297641 |
| SCIELO_PID | S0034-89102015000100406 |
| Language | EN |
| References cited | 40 |
OBJECTIVE To analyze whether gender influence survival results of kidney transplant grafts and patients.METHODS Systematic review with meta-analysis of cohort studies available on Medline (PubMed), LILACS, CENTRAL, and Embase databases, including manual searching and in the grey literature. The selection of studies and the collection of data were conducted twice by independent reviewers, and disagreements were settled by a third reviewer. Graft and patient survival rates were evaluated as effectiveness measurements. Meta-analysis was conducted with the Review Manager® 5.2 software, through the application of a random effects model. Recipient, donor, and donor-recipient gender comparisons were evaluated.RESULTS : Twenty-nine studies involving 765,753 patients were included. Regarding graft survival, those from male donors were observed to have longer survival rates as compared to the ones from female donors, only regarding a 10-year follow-up period. Comparison between recipient genders was not found to have significant differences on any evaluated follow-up periods. In the evaluation between donor-recipient genders, male donor-male recipient transplants were favored in a statistically significant way. No statistically significant differences were observed in regards to patient survival for gender comparisons in all follow-up periods evaluated.CONCLUSIONS The quantitative analysis of the studies suggests that donor or recipient genders, when evaluated isolatedly, do not influence patient or graft survival rates. However, the combination between donor-recipient genders may be a determining factor for graft survival
Biology · Cohort study · Kidney · Kidney transplantation · MEDLINE · Meta-analysis · Random effects model · Survival analysis · Demography · Internal Medicine · Medicine · Organ Donation and Transplantation · Renal and Vascular Pathologies · Renal Transplantation Outcomes and Treatments · Surgery
| Citation velocity | historical |
|---|---|
| Highly cited | No |