Atrial fibrillation as a risk factor for stroke
A retrospective cohort study of hospitalized Medicare beneficiaries
Bibliographic Data
| ID | 11023016 |
|---|---|
| Authors | Zuyi Yuan (0000-0002-4141-0298, Case Western Reserve University), S Bowlin, Steven J Bowlin (Case Western Reserve University), Douglas Einstadter (0000-0002-7673-4436, Cancer Research And Biostatistics), Randall D Cebul (Cancer Research And Biostatistics), A R Conners, AL Conners (University of Virginia), Alfred A Rimm (Cancer Research And Biostatistics) |
| Year | 1998 |
| Volume | 88 |
| Issue | 3 |
| Pages | 395-400 |
| Publication date | 1998-03-01 |
| Peer Reviewed | Yes |
| Open Access | No |
| Type | ARTICLE |
| Venue | American Journal of Public Health (JOURNAL) |
| Journal identifiers | ISSN: 0090-0036 • E-ISSN: 1541-0048 |
| Publisher | American Public Health Association (PUBLISHER • US) |
| DOI | 10.2105/ajph.88.3.395 |
| PMID | 9518970 |
| OpenAlex | W2089124341 |
| Language | EN |
| Citations received | 1 |
| References cited | 29 |
OBJECTIVES: This study examined the relationship between atrial fibrillation and (1) stroke and (2) all-cause mortality. METHODS: All eligible Medicare patients older than 65 years of age hospitalized in 1985 were followed up for 4 years. Kaplan-Meier and Cox proportional hazards models were used for assessment of risk of stroke and mortality. RESULTS: A total of 4,282,607 eligible Medicare patients were hospitalized in 1985. The mean age was 76.1 (+/- 7.7) years; 58.7% were female; 7.2% were Black; and 8.4% had a diagnosis of atrial fibrillation. During the follow-up period, 66,063 patients (32.6/1000 person-years) developed nonembolic stroke and 7285 (3.6/1000 person-years) developed embolic stroke. After adjustment for age, race, sex, and comorbid conditions, atrial fibrillation remained a significant risk factor for both nonembolic stroke (relative risk [RR] = 1.56) and embolic stroke (RR = 5.80) and for mortality (RR = 1.31). Approximately 4.5% of nonembolic and 28.7% of embolic strokes among hospitalized Medicare patients aged 65 years and older were attributable to atrial fibrillation. CONCLUSIONS: This study demonstrates that atrial fibrillation is associated with an appreciable increase in the risk of stroke (both embolic and nonembolic) and in the risk of mortality from all causes
Atrial fibrillation · Cohort · Cohort study · Ischemic stroke · Retrospective cohort study · Risk factor · Stroke (engine) · Stroke risk · Atrial Fibrillation Management and Outcomes · Cardiovascular and Diving-Related Complications · Cerebrovascular and Carotid Artery Diseases · Emergency Medicine · Internal Medicine · Medicine
| Unique citing works | 1 |
|---|---|
| Citations per year | 0,05 |
| Citation span | 2005 - 2005 (1) |
| Citation velocity | historical |
| Highly cited | No |
| Citation types | Neutral: 1 |