Effects of paternal occupational exposure on spontaneous abortions
Bibliographic Data
| ID | 11023397 |
|---|---|
| Authors | M L Lindbohm (Finnish Institute of Occupational Health), Kari Hemminki (0000-0002-2769-3316), Michèle G Bonhomme (Finnish Institute of Occupational Health), Ahti Anttila (0000-0002-8484-7043, Finnish Institute of Occupational Health), Kaarina Rantala (Finnish Institute of Occupational Health), Pirjo Heikkilä (0000-0002-5055-5165, Finnish Institute of Occupational Health), M J Rosenberg (0000-0002-9924-304X, Finnish Institute of Occupational Health) |
| Year | 1991 |
| Volume | 81 |
| Issue | 8 |
| Pages | 1029-1033 |
| Publication date | 1991-08-01 |
| Peer Reviewed | Yes |
| Open Access | No |
| Type | ARTICLE |
| Venue | American Journal of Public Health (JOURNAL) |
| Journal identifiers | ISSN: 0090-0036 • E-ISSN: 1541-0048 |
| Publisher | American Public Health Association (PUBLISHER • US) |
| DOI | 10.2105/ajph.81.8.1029 |
| PMID | 1853994 |
| OpenAlex | W1982658540 |
| Language | EN |
| Citations received | 1 |
| References cited | 12 |
BACKGROUND: Paternal exposure to mutagenic agents has been suggested to affect pregnancy outcome adversely. METHODS: A nationwide data base of medically diagnosed spontaneous abortions and other pregnancies and national census data was used to evaluate the effects of men's occupational exposures on risk of spontaneous abortion in 99,186 pregnancies in Finland. Census data from the years 1975 and 1980 provided information about the occupation, industry, and socioeconomic status. A job-exposure classification was developed to classify women and their husbands according to possible occupational exposures on the basis of their occupational title and industry. RESULTS: In 10% of the pregnancies, the husband was exposed to one or more of the mutagens, and the rate of spontaneous abortion was unaffected (OR = 1.0). Of the 25 specific mutagenic exposures evaluated, paternal exposure to four (ethylene oxide, rubber chemicals, solvents used in refineries, and solvents used in the manufacturing of rubber products) was associated with an increased relative risk of spontaneous abortion. In addition, the risk of spontaneous abortion was higher among wives of rubber products workers than among unexposed men. CONCLUSIONS: Although there is some biological rationale for the findings of this study, these findings need to be confirmed by studies in which individual exposures can be measured directly
Abortion · Biology · Environmental health · Obstetrics · Occupational exposure · Occupational medicine · Population · Pregnancy · Socioeconomic status · Carcinogens and Genotoxicity Assessment · Effects and risks of endocrine disrupting chemicals · Medicine · Sperm and Testicular Function · Toxicology
| Unique citing works | 1 |
|---|---|
| Citations per year | 0,03 |
| Citation span | 1997 - 1997 (1) |
| Citation velocity | historical |
| Highly cited | No |
| Citation types | Neutral: 1 |