Individual Participant Data Meta-Analysis of Mechanical Workplace Risk Factors and Low Back Pain

Bibliographic Data

ID11023609
AuthorsLauren E Griffith (0000-0002-2794-9692, Lauren E. Griffith, Harry S. Shannon, and Stephen D. Walter are with the Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario. Richard P. Wells is with the Department of Kinesiology, University of Waterloo, Waterloo, Ontario. Donald C. Cole and Pierre Côté are with the Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario. John Frank is with the School of Clinical Science and Community Health, University of Edinburgh, Edinburgh, UK. Sheilah...), Harry S Shannon (0000-0002-7507-427X, Lauren E. Griffith, Harry S. Shannon, and Stephen D. Walter are with the Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario. Richard P. Wells is with the Department of Kinesiology, University of Waterloo, Waterloo, Ontario. Donald C. Cole and Pierre Côté are with the Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario. John Frank is with the School of Clinical Science and Community Health, University of Edinburgh, Edinburgh, UK. Sheilah...), Richard P Wells (Lauren E. Griffith, Harry S. Shannon, and Stephen D. Walter are with the Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario. Richard P. Wells is with the Department of Kinesiology, University of Waterloo, Waterloo, Ontario. Donald C. Cole and Pierre Côté are with the Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario. John Frank is with the School of Clinical Science and Community Health, University of Edinburgh, Edinburgh, UK. Sheilah...), Stephen D Walter (0000-0003-4157-8928, Lauren E. Griffith, Harry S. Shannon, and Stephen D. Walter are with the Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario. Richard P. Wells is with the Department of Kinesiology, University of Waterloo, Waterloo, Ontario. Donald C. Cole and Pierre Côté are with the Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario. John Frank is with the School of Clinical Science and Community Health, University of Edinburgh, Edinburgh, UK. Sheilah...), Donald C Cole (0000-0002-1009-603X, Lauren E. Griffith, Harry S. Shannon, and Stephen D. Walter are with the Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario. Richard P. Wells is with the Department of Kinesiology, University of Waterloo, Waterloo, Ontario. Donald C. Cole and Pierre Côté are with the Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario. John Frank is with the School of Clinical Science and Community Health, University of Edinburgh, Edinburgh, UK. Sheilah...), Pierre Côté (Lauren E. Griffith, Harry S. Shannon, and Stephen D. Walter are with the Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario. Richard P. Wells is with the Department of Kinesiology, University of Waterloo, Waterloo, Ontario. Donald C. Cole and Pierre Côté are with the Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario. John Frank is with the School of Clinical Science and Community Health, University of Edinburgh, Edinburgh, UK. Sheilah...), John Frank (0000-0001-9289-9989, Lauren E. Griffith, Harry S. Shannon, and Stephen D. Walter are with the Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario. Richard P. Wells is with the Department of Kinesiology, University of Waterloo, Waterloo, Ontario. Donald C. Cole and Pierre Côté are with the Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario. John Frank is with the School of Clinical Science and Community Health, University of Edinburgh, Edinburgh, UK. Sheilah...), Sheilah Hogg-Johnson (Lauren E. Griffith, Harry S. Shannon, and Stephen D. Walter are with the Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario. Richard P. Wells is with the Department of Kinesiology, University of Waterloo, Waterloo, Ontario. Donald C. Cole and Pierre Côté are with the Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario. John Frank is with the School of Clinical Science and Community Health, University of Edinburgh, Edinburgh, UK. Sheilah...), Lacey E Langlois (Lauren E. Griffith, Harry S. Shannon, and Stephen D. Walter are with the Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario. Richard P. Wells is with the Department of Kinesiology, University of Waterloo, Waterloo, Ontario. Donald C. Cole and Pierre Côté are with the Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario. John Frank is with the School of Clinical Science and Community Health, University of Edinburgh, Edinburgh, UK. Sheilah...)
Year2012
Volume102
Issue2
Pages309-318
Publication date2012-02-01
Peer ReviewedYes
Open AccessNo
TypeARTICLE
VenueAmerican Journal of Public Health (JOURNAL)
Journal identifiersISSN: 0090-0036 • E-ISSN: 1541-0048
PublisherAmerican Public Health Association (PUBLISHER • US)
DOI10.2105/ajph.2011.300343
PMID22390445
PMCIDPMC3483985
LanguageEN
Citations received3
References cited78

Objectives. We used individual participant data from multiple studies to conduct a comprehensive meta-analysis of mechanical exposures in the workplace and low back pain. Methods. We conducted a systematic literature search and contacted an author of each study to request their individual participant data. Because outcome definitions and exposure measures were not uniform across studies, we conducted 2 substudies: (1) to identify sets of outcome definitions that could be combined in a meta-analysis and (2) to develop methods to translate mechanical exposure onto a common metric. We used generalized estimating equation regression to analyze the data. Results. The odds ratios (ORs) for posture exposures ranged from 1.1 to 2.0. Force exposure ORs ranged from 1.4 to 2.1. The magnitudes of the ORs differed according to the definition of low back pain, and heterogeneity was associated with both study-level and individual-level characteristics. Conclusions. We found small to moderate ORs for the association of mechanical exposures and low back pain, although the relationships were complex. The presence of individual-level OR modifiers in such an area can be best understood by conducting a meta-analysis of individual participant data

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