Preventing Mother-to-Child Transmission of HIV in Resource-Limited Settings

The Elizabeth Glaser Pediatric Aids Foundation Experience

Datos Bibliográficos

ID11023625
AutoresAllison Spensley (Allison Spensley, Tabitha Sripipatana, Chuck Hoblitzelle, Joanna Robinson, and Catherine Wilfert are with the Elizabeth Glaser Pediatric AIDS Foundation, Santa Monica, CA. Abigail Norris Turner is with the University of North Carolina, Chapel Hill.), Tabitha Sripipatana (Allison Spensley, Tabitha Sripipatana, Chuck Hoblitzelle, Joanna Robinson, and Catherine Wilfert are with the Elizabeth Glaser Pediatric AIDS Foundation, Santa Monica, CA. Abigail Norris Turner is with the University of North Carolina, Chapel Hill.), Abigail Norris Turner (0000-0003-2463-6399, Allison Spensley, Tabitha Sripipatana, Chuck Hoblitzelle, Joanna Robinson, and Catherine Wilfert are with the Elizabeth Glaser Pediatric AIDS Foundation, Santa Monica, CA. Abigail Norris Turner is with the University of North Carolina, Chapel Hill.), Chuck Hoblitzelle (Allison Spensley, Tabitha Sripipatana, Chuck Hoblitzelle, Joanna Robinson, and Catherine Wilfert are with the Elizabeth Glaser Pediatric AIDS Foundation, Santa Monica, CA. Abigail Norris Turner is with the University of North Carolina, Chapel Hill.), Joanna L Robinson (0000-0002-4416-2330, Allison Spensley, Tabitha Sripipatana, Chuck Hoblitzelle, Joanna Robinson, and Catherine Wilfert are with the Elizabeth Glaser Pediatric AIDS Foundation, Santa Monica, CA. Abigail Norris Turner is with the University of North Carolina, Chapel Hill.), Joanna Robinson (Elizabeth Glaser Pediatric AIDS Foundation), Catherine Wilfert (Allison Spensley, Tabitha Sripipatana, Chuck Hoblitzelle, Joanna Robinson, and Catherine Wilfert are with the Elizabeth Glaser Pediatric AIDS Foundation, Santa Monica, CA. Abigail Norris Turner is with the University of North Carolina, Chapel Hill.), Catherine M Wilfert (Elizabeth Glaser Pediatric AIDS Foundation)
Año2009
Volumen99
Número4
Páginas631-637
Fecha de publicación2009-04-01
Peer ReviewedSí
Open AccessNo
TipoARTICLE
RevistaAmerican Journal of Public Health (JOURNAL)
Identificadores de la revistaISSN: 0090-0036 • E-ISSN: 1541-0048
EditorialAmerican Public Health Association (PUBLISHER • US)
DOI10.2105/ajph.2007.114421
PMID18703458
PMCIDPMC2661479
OpenAlexW2088107908
IdiomaEN
Citas recibidas6
Referencias citadas20

Objectives. In September 1999, the Elizabeth Glaser Pediatric AIDS Foundation initiated a multicountry, service-based programmatic effort in the developing world to reduce perinatally acquired HIV infection. We review 61⁄2 years of one of the world's largest programs for the prevention of mother-to-child transmission (PMTCT) of HIV. Methods. Each PMTCT facility records patient data in antenatal clinics and labor and delivery settings about counseling, testing, HIV status, and antiretroviral prophylaxis and submits the data to foundation staff. Results. More than 2.6 million women have accessed foundation-affiliated services through June 2006. Overall, 92.9% of women who received antenatal care or were eligible for PMTCT services in labor and delivery have been counseled, and 82.8% of those counseled accepted testing. Among women identified as HIV positive, 75.0% received antiretroviral prophylaxis (most a single dose of nevirapine), as did 45.6% of their infants. Conclusions. The foundation's experience has demonstrated that opt-out testing, supplying mothers with medication at time of diagnosis, and providing the infant dose early have measurably improved program efficiency. PMTCT should be viewed as an achievable paradigm and an essential part of the continuum of care

Antiretroviral therapy · Developing country · Family medicine · Human immunodeficiency virus (HIV) · Nevirapine · Transmission (telecommunications) · Viral load · Adolescent Sexual and Reproductive Health · Global Maternal and Child Health · HIV/AIDS Research and Interventions · Medicine · Pediatrics