Maternal serum alpha-fetoprotein screening
A cost-benefit analysis
Bibliographic Data
| ID | 11025569 |
|---|---|
| Authors | Peter M Layde, S D von Allmen, Godfrey P Oakley (0000-0003-2185-3929) |
| Year | 1979 |
| Volume | 69 |
| Issue | 6 |
| Pages | 566-573 |
| Publication date | 1979-06-01 |
| Peer Reviewed | Yes |
| Open Access | No |
| Type | ARTICLE |
| Venue | American Journal of Public Health (JOURNAL) |
| Journal identifiers | ISSN: 0090-0036 • E-ISSN: 1541-0048 |
| Publisher | American Public Health Association (PUBLISHER • US) |
| DOI | 10.2105/ajph.69.6.566 |
| PMID | 87134 |
| OpenAlex | W2096260031 |
| Language | EN |
| Citations received | 5 |
| References cited | 12 |
The prenatal detection of fetal neural tube defects (NTD) is now possible by means of a multi-tiered program utilizing maternal serum alpha-fetoprotein (MSAFP) screening coupled with ultrasonography and amniocentesis where indicated. This paper considers the economic consequences of screening for fetal NTD a theoretical cohort of 100,000 pregnant women at risk of having an affected fetus who would elect to terminate their pregnancies if an affected fetus were found. The cost of the program was balanced against the benefits of the program, such as the averted costs of institutionalization, medical care, and the like. The total cost of the program to screen 100,000 such women was calculated to be $2,047,780, or slightly over $20 per woman screened, while the total economic benefits exceeded $4,000,000
Amniocentesis · Biology · Cohort · Cost effectiveness · Cost–benefit analysis · Environmental health · Fetus · Gynecology · Neural tube defect · Obstetrics · Population · Pregnancy · Prenatal care · Prenatal diagnosis · Internal Medicine · Medicine · Prenatal Screening and Diagnostics · Pediatrics
A Cost-Effectiveness Analysis of Amniocentesis and Chorionic Villus Sampling for Prenatal Genetic Testing
Cost-Justification Analysis of Prenatal Maternal Serum Alpha-feto Protein Screening
Measuring the benefits of screening for open neural tube defects
Alpha-fetoprotein and the prenatal detection of neural tube defects
An economic appraisal of the benefits of screening for open spina bifida
| Unique citing works | 5 |
|---|---|
| Citations per year | 0,11 |
| Citation span | 1979 - 1994 (16) |
| Citation velocity | historical |
| Highly cited | No |
| Citation types | Neutral: 3 |