Aplastic anemia in rural Thailand

Its association with grain farming and agricultural pesticide exposure. Aplastic Anemia Study Group

Bibliographic Data

ID11026659
AuthorsSurapol Issaragrisil (0000-0002-8924-0646, Siriraj Hospital), Kanchana Chansung, David W Kaufman (0000-0002-2150-5070), Jittima Sirijirachai, T Thamprasit, Neal S Young (0009-0007-0999-2519)
Year1997
Volume87
Issue9
Pages1551-1554
Publication date1997-09-01
Open AccessNo
TypeARTICLE
VenueAmerican Journal of Public Health (JOURNAL)
Journal identifiersISSN: 0090-0036 • E-ISSN: 1541-0048
PublisherAmerican Public Health Association (PUBLISHER • US)
DOI10.2105/ajph.87.9.1551
PMID9314815
OpenAlexW2049222157
LanguageEN
References cited4

OBJECTIVES: A population-based case-control study was conducted to elucidate the incidence and etiology of aplastic anemia in Thailand. METHODS: Case patients and hospital control patients were enrolled in three regions from 1989 to 1994; data were collected by interview. RESULTS: Forty-six percent of 81 case patients and 19% of 295 control patients from Khonkaen were grain farmers (estimated relative risk [RR] = 2.7, 95% confidence interval [CI] = 1.4, 5.2). Sixteen percent of case patients and 6% of control patients used agricultural pesticides (estimated RR = 2.7, 95% CI = 1.1, 6.6). The association with grain farming remained among those not exposed to pesticides. In Songkla, 16% of 43 case patients and 2% of 181 control patients were grain farmers (crude RR estimate = 11, 95% CI = 3.4, 35). CONCLUSIONS: The relation of aplastic anemia to grain farming may partly explain the high incidence of aplastic anemia in Thailand

Anemia · Aplastic anemia · Confidence interval · Environmental health · Etiology · Incidence (geometry) · Relative risk · Hematopoietic Stem Cell Transplantation · Internal Medicine · Medicine · Reproductive Biology and Fertility · Sperm and Testicular Function · Pediatrics

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