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Evaluation of the relationship of sodium in drinking water and toxemia of pregnancy

Bibliographic Data

ID11028111
AuthorsRobert Jones (0000-0002-6793-6503), R F JONES, Irina I Cech, Alfonso H Holguin, R J Hardy
Year1979
Volume69
Issue9
Pages917-921
Publication date1979-09-01
Open AccessNo
TypeARTICLE
VenueAmerican Journal of Public Health (JOURNAL)
Journal identifiersISSN: 0090-0036 • E-ISSN: 1541-0048
PublisherAmerican Public Health Association (PUBLISHER • US)
DOI10.2105/ajph.69.9.917
PMID474848
OpenAlexW1968212897
LanguageEN
Citations received1
References cited9

This study is a retrospective case comparison analysis of the relationship of water-borne Na+ and toxemia of pregnancy as a part of a continuous investigation at our facility on the role of various water constituents in human chronic disease. Five hundred thirty-seven toxemic pregnant women delivered at Jefferson Davis Hospital, Houston, Texas, during 1976 were matched by age, race, obstetrical history, and month of delivery to 537 non-toxemic controls. Sodium concentration in each patient's drinking water was derived, based on her address, from earlier prepared maps of sodium distribution in Houston's water supplies. Paired t-tests were performed to compare the Na+ levels, which varied from 19 to 250 mg/l in water supplies of cases and controls. Odds ratio analysis was used to test for the presence of a gradient in occurrence of toxemia in parallel with the gradient of Na+. No significant impact of water-borne Na+ in the indicated range was observed. Further studies incorporating still higher ranges are contemplated

Biology · Obstetrics · Odds ratio · Pregnancy · Sodium · Chemistry · Internal Medicine · Medicine · Renal function and acid-base balance

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Highly citedNo

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