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The effect of congenital anomalies on mortality risk in white and black infants

Bibliographic Data

ID11028801
AuthorsLorraine Halinka Malcoe (0000-0001-8778-9443), Gary M Shaw (0000-0001-7438-4914), Edward J Lammer, Allen Herman, A A Herman
Year1999
Volume89
Issue6
Pages887-892
Publication date1999-06-01
Peer ReviewedYes
Open AccessNo
TypeARTICLE
VenueAmerican Journal of Public Health (JOURNAL)
Journal identifiersISSN: 0090-0036 • E-ISSN: 1541-0048
PublisherAmerican Public Health Association (PUBLISHER • US)
DOI10.2105/ajph.89.6.887
PMID10358680
OpenAlexW2101039884
LanguageEN
Citations received1
References cited13

OBJECTIVES: This population-based study examined the effect of all major congenital anomalies on the mortality of White and Black infants by infant sex, birthweight, gestational age, and lethality of the anomaly. The study also determined the total contribution of anomalies to infant mortality. METHODS: California Birth Defects Monitoring Program data were merged with linked birth-death files for 278,646 singleton non-Hispanic White and Black infants born in 1983 through 1986. Malformed infants were compared with nonmalformed infants to determine the effect of anomalies on mortality. RESULTS: The presence of any congenital anomaly increased mortality 9.0-fold (95% CI = 7.3, 11.1) for Black infants and 17.8-fold (95% CI = 16.2, 19.6) for White infants. Even "non-lethal" anomalies increased mortality up to 8.9-fold. Overall, anomalies contributed to 33% of White infant deaths, to 19% of Black infant deaths, and to over 60% of deaths among Black and White neonates weighing over 1499 g. CONCLUSIONS: The contribution of congenital anomalies to mortality of both low- (

Biology · Environmental health · White (mutation) · Demography · Folate and B Vitamins Research · Genetics · Maternal and Neonatal Healthcare · Medicine · Prenatal Screening and Diagnostics · Pediatrics

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Unique citing works1
Citations per year0.05
Citation span2006 - 2006 (1)
Citation velocityhistorical
Highly citedNo
Citation typesNeutral: 1

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