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Reduced risk of hepatitis B and hepatitis C among injection drug users in the Tacoma syringe exchange program

Bibliographic Data

ID11029210
AuthorsHolly Hagan (0000-0002-9020-9232, Public Health – Seattle & King County), D C Jarlais, Des Jarlais, R Friedman (0000-0003-2083-1226, Public Health – Seattle & King County), S R Friedman, David Purchase (Public Health – Seattle & King County), M J Alter (Public Health – Seattle & King County)
Year1995
Volume85
Issue11
Pages1531-1537
Publication date1995-11-01
Peer ReviewedYes
Open AccessNo
TypeARTICLE
VenueAmerican Journal of Public Health (JOURNAL)
Journal identifiersISSN: 0090-0036 • E-ISSN: 1541-0048
PublisherAmerican Public Health Association (PUBLISHER • US)
DOI10.2105/ajph.85.11.1531
PMID7485666
OpenAlexW2046844674
LanguageEN
Citations received45
References cited28

OBJECTIVES. This case-control study examined the association between syringe exchange use and hepatitis B and C in injection drug users. METHODS. Case patients included 28 injection drug users with acute hepatitis B and 20 with acute hepatitis C reported to the health department in a sentinel hepatitis surveillance county; control subjects were injection drug users with no markers of exposure to hepatitis B or C (n = 38 and 26, respectively) attending health department services during the same period. Data were abstracted from clinic records. RESULTS. Seventy-five percent of case patients with hepatitis B and 26% of control subjects had never used the exchange; similar proportions were found for the hepatitis C case and control groups. After adjustment for demographic characteristics and duration of injecting drugs, nonuse of the exchange was associated with a sixfold greater risk of hepatitis B (odds ratio [OR] = 5.5; 95% confidence interval [CI] = 1.5, 20.4) and a sevenfold greater risk of hepatitis C (OR = 7.3; 95% CI = 1.6, 32.8). CONCLUSIONS. The results suggest that use of the exchange led to a significant reduction in hepatitis B and hepatitis C in the county and may have also prevented a substantial proportion of human immunodeficiency virus infections in injection drug users

Confidence interval · Drug · Hepatitis · Hepatitis B · Hepatitis B virus · Hepatitis C · Odds ratio · Psychiatry · Syringe · Virus · Hepatitis B Virus Studies · Hepatitis C virus research · HIV, Drug Use, Sexual Risk · Immunology · Internal Medicine · Medicine · Pharmacology · Virology

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Unique citing works45
Citations per year1,45
Citation span1995 - 2026 (32)
Citation velocitycurrent
Highly citedNo
Citation typesNeutral: 44

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