Smoking and Cognitive Decline Among Middle-Aged Men and Women

The Doetinchem Cohort Study

Bibliographic Data

ID11029478
AuthorsAstrid CJ Nooyens (0000-0003-1412-3338, National Institute for Public Health and the Environment), Astrid C J Nooyens (The authors are with the Centre for Prevention and Health Services Research, National Institute for Public Health and the Environment (RIVM), Bilthoven, Netherlands.), Boukje M van Gelder (The authors are with the Centre for Prevention and Health Services Research, National Institute for Public Health and the Environment (RIVM), Bilthoven, Netherlands.), W M Monique Verschuren (0000-0003-2134-4227, The authors are with the Centre for Prevention and Health Services Research, National Institute for Public Health and the Environment (RIVM), Bilthoven, Netherlands.)
Year2008
Volume98
Issue12
Pages2244-2250
Publication date2008-12-01
Peer ReviewedYes
Open AccessNo
TypeARTICLE
VenueAmerican Journal of Public Health (JOURNAL)
Journal identifiersISSN: 0090-0036 • E-ISSN: 1541-0048
PublisherAmerican Public Health Association (PUBLISHER • US)
DOI10.2105/ajph.2007.130294
PMID18923116
PMCIDPMC2636537
OpenAlexW2001705627
LanguageEN
Citations received8
References cited32

Objectives. We studied the effect of smoking on cognitive decline over a 5-year period at middle age (43 to 70 years). Methods. In the Doetinchem Cohort Study, 1964 men and women in the Netherlands were examined for cognitive function at baseline and 5 years later. The association between smoking status and memory function, speed of cognitive processes, cognitive flexibility, and global cognitive function were assessed. Results. At baseline, smokers scored lower than never smokers in global cognitive function, speed, and flexibility. At 5-year follow-up, decline among smokers was 1.9 times greater for memory function, 2.4 times greater for cognitive flexibility, and 1.7 times greater for global cognitive function than among never smokers. Among ever smokers, the declines in all cognitive domains were larger with increasing number of pack-years smoked. Conclusions. Interventions to prevent or stop people from smoking may postpone cognitive decline in middle-aged persons

Cognition · Cognitive decline · Cognitive flexibility · Cohort · Cohort study · Dementia · Effects of sleep deprivation on cognitive performance · Psychiatry · Psychological intervention · Dementia and Cognitive Impairment Research · Demography · Internal Medicine · Medicine · Nicotinic Acetylcholine Receptors Study · Smoking Behavior and Cessation · Gerontology

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