Increasing rubella seronegativity despite a compulsory school law
Bibliographic Data
| ID | 11030185 |
|---|---|
| Authors | Timothy R Schum (Medical College of Wisconsin), D B Nelson, M A Duma, Marcin Duma, G V Sedmak, Gerald Sedmak |
| Year | 1990 |
| Volume | 80 |
| Issue | 1 |
| Pages | 66-69 |
| Publication date | 1990-01-01 |
| Open Access | No |
| Type | ARTICLE |
| Venue | American Journal of Public Health (JOURNAL) |
| Journal identifiers | ISSN: 0090-0036 • E-ISSN: 1541-0048 |
| Publisher | American Public Health Association (PUBLISHER • US) |
| DOI | 10.2105/ajph.80.1.66 |
| PMID | 2293805 |
| OpenAlex | W2023313253 |
| Language | EN |
| Citations received | 2 |
| References cited | 18 |
To determine if lower rubella susceptibility persisted five to seven years after immunization legislation, we retrospectively reviewed the serologic status of 341 outpatients from 1985 to 1987 in an inner-city school age population. Seronegative rates increased significantly during the two-year study period from 4.2 to 24.5 percent (17 percent overall). (Beta = 6.8%, 95% CI = 3.3, 10.3). Charts were reviewed for 57 of 58 seronegative and 114 seropositive controls. Estimates were then made to the population of 341 subjects. Those with documented rubella immunization had a seronegative rate of 13 percent compared to 19 percent if the immunization status was unknown. For patients who received care in our clinic for less than two years, 32 percent were seronegative compared to 10 percent for those treated greater than or equal to 2 years (odds ratio = 0.31, 95% CI = 0.16, 0.60). Among patients immunized in 1977 or 1978, 33 percent were seronegative compared to 7 percent immunized at other times (OR = 0.21, 95% CI = 0.07, 0.63). Factors associated with increased rubella seronegativity include immunization in 1977 or 1978 and lack of continuity of care in our clinic. Much of the increase remains unexplained
Antibody · Environmental health · Immunization · Measles · Odds ratio · Population · Rubella · Rubella vaccine · Serology · Vaccination · Demography · Immunology · Internal Medicine · Medicine · Rabies epidemiology and control · Virology and Viral Diseases · Zoonotic diseases and public health · Pediatrics
| Highly cited | No |
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