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Spermicide use and Down's syndrome

Datos Bibliográficos

ID11030342
AutoresKenneth J Rothman (0000-0003-2398-1705, autor de correspondencia)
Año1982
Volumen72
Número4
Páginas399-401
Fecha de publicación1982-04-01
Peer ReviewedSí
Open AccessNo
TipoARTICLE
RevistaAmerican Journal of Public Health (JOURNAL)
Identificadores de la revistaISSN: 0090-0036 • E-ISSN: 1541-0048
EditorialAmerican Public Health Association (PUBLISHER • US)
DOI10.2105/ajph.72.4.399
PMID6461262
OpenAlexW1995135603
IdiomaEN
Citas recibidas9
Referencias citadas9

A connection has been suggested between use of vaginal spermicides and the occurrence of Down's syndrome among offspring born to women who used these contraceptive agents. This hypothesis was evaluated with data from a case-control study of congenital heart disease, which included among the subjects 16 infants with Down's syndrome. The estimated ratio of the proportion of Down's syndrome births among spermicide users to the proportion in non-users was 3.6, with a 90 per cent confidence interval of 1.2 to 9.0, thus providing a tentative confirmation of the hypothesis

Confidence interval · Down syndrome · Environmental health · Family planning · Gynecology · Obstetrics · Offspring · Population · Pregnancy · Research methodology · Spermicide · Global Maternal and Child Health · Internal Medicine · Medicine

  • Dentro del laberinto

    Open Access•Vania Salles, Rodolfo Tuirán•Estudios Demográficos y Urbanos•1997

  • Contraceptive Perceptions and Method Choice Among Young Single Women in the United States

    Koray Tanfer, Emily Rosenbaum•Studies in Family Planning•1986

  • Dr. Rothman's Reply

    Kenneth J Rothman•American Journal of Public Health•1982

  • On the comparison of effects

    William Thompson, W D Thompson•American Journal of Public Health•1987

  • Confidence intervals exclude nothing

    C Poole•American Journal of Public Health•1987

  • Spermicides and Down's syndrome

    P F Van Peenen, N Nelson et al.•American Journal of Public Health•1982

  • Spermicide use and pregnancy outcome

    B Strobino, Barbara A Strobino et al.•American Journal of Public Health•1988

  • Beyond the confidence interval

    C Poole•American Journal of Public Health•1987

  • Mr. Poole's Response

    Charles Poole•American Journal of Public Health•1987

  • Sexual Activity, Contraceptive Use and Pregnancy Among Metropolitan-Area Teenagers

    Melvin Zelnik, John F Kantner•Family Planning Perspectives•1980

  • Spermicides and Down's syndrome

    P F Van Peenen, N Nelson et al.•American Journal of Public Health•1982

  • Illegitimate and premaritally conceived first births in Massachusetts, 1966–1968

    Elizabeth Murphy Whelan•Social Biology•1972

Obras citantes distintas9
Citas por año0,2
Intervalo de citas1982 - 1997 (16)
Velocidad de citaciónhistorical
Altamente citadoNo
Tipos de citaNeutras: 7
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