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Why clinical trials of Aids vaccines are premature

Bibliographic Data

ID11033103
AuthorsWendy K Mariner (0000-0001-5176-5917, Boston University, corresponding author)
Year1989
Volume79
Issue1
Pages86-91
Publication date1989-01-01
Peer ReviewedYes
Open AccessNo
TypeARTICLE
VenueAmerican Journal of Public Health (JOURNAL)
Journal identifiersISSN: 0090-0036 • E-ISSN: 1541-0048
PublisherAmerican Public Health Association (PUBLISHER • US)
DOI10.2105/ajph.79.1.86
PMID2642371
OpenAlexW2045359906
LanguageEN
Citations received2
References cited25

Considering the current state of scientific knowledge and the fact\nthat no relevant animal model exists for demonstrating a vaccine's probable\nefficacy, the fundamental prerequisites for testing experimental AIDS vaccines\nin human beings have not been met. The ethical obligations of informed\nconsent, patient confidentiality, and the balancing of risks and benefits are\nexamined in a call for more public debate on the issue before clinical trials\nare begun. (KIE abstract)

Clinical trial · Environmental health · Family medicine · HIV Research and Treatment · HIV/AIDS Research and Interventions · Internal Medicine · Medicine · T-cell and Retrovirus Studies

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    Wendy K Mariner•American Journal of Public Health•1990

  • HIV vaccine trials

    Karin Meyers, David S Metzger et al.•American Journal of Public Health•1994

  • Scientific Value and Validity as Ethical Requirements for Research

    Benjamin Freedman•IRB Ethics and Human Research•1987

  • Report of the Presidential Commission on the Human Immunodeficiency Virus Epidemic

    John Bongaarts•Population and Development Review•1988

Unique citing works2
Citations per year0,06
Citation span1990 - 1994 (5)
Citation velocityhistorical
Highly citedNo
Citation typesNeutral: 2

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