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The risk of hip fracture in postmenopausal females with or without estrogen drug exposure

Bibliographic Data

ID11036581
AuthorsRobert E Johnson (0000-0002-0195-619X), Elmer E Specht
Year1981
Volume71
Issue2
Pages138-144
Publication date1981-02-01
Peer ReviewedYes
Open AccessNo
TypeARTICLE
VenueAmerican Journal of Public Health (JOURNAL)
Journal identifiersISSN: 0090-0036 • E-ISSN: 1541-0048
PublisherAmerican Public Health Association (PUBLISHER • US)
DOI10.2105/ajph.71.2.138
PMID7457682
OpenAlexW2105589075
LanguageEN
Citations received4
References cited18

This study estimated the risk of hip fracture among postmenopausal females with and without estrogen drug exposure. The Kaiser-Permanente Medical Care Program in Portland, Oregon served as the setting and medical records the source of data. A retrospective case-control method that matched each female member hospitalized with a hip fracture (N = 168) between 1965-1975 with two control female members hospitalized for reasons other than a hip fracture was used. The estrogen exposure rate of cases was 29.2 per cent and of controls 36.0 per cent. The risk of hip fracture was reduced with postmenopausal and prefracture estrogen exposure (RML = 0.72, 95 per cent CL: 0.48-1.09). However, the number of cases was sufficient only to detect a reduction in risk of about 50 per cent or greater. A possible protective effect from estrogens was also suggested with oral estrogen exposure and with longer lengths of estrogen exposure

Confidence interval · Estrogen · Hip fracture · Medical record · Osteoporosis · Postmenopausal women · Relative risk · Bone health and osteoporosis research · Internal Medicine · Medicine

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Unique citing works4
Citations per year0,09
Citation span1981 - 1984 (4)
Citation velocityhistorical
Highly citedNo
Citation typesNeutral: 4

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