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Principal component analysis of socioeconomic factors and their association with malaria and arbovirus risk in Tanzania

A sensitivity analysis

Bibliographic Data

ID11173281
AuthorsEsha Homenauth (University of Ottawa), Debora Kajeguka (Department of Microbiology and Immunology, Kilimanjaro Christian Medical University College, Moshi, Tanzania), Debora C Kajeguka (0000-0003-4341-5938, Kilimanjaro Christian Medical Centre), Manisha A Kulkarni (0000-0002-5084-4960, University of Ottawa, corresponding author)
Year2017
Volume71
Issue11
Pages1046-1051
Publication date2017-11-01
Peer ReviewedYes
Open AccessNo
TypeARTICLE
VenueJournal of Epidemiology and Community Health (JOURNAL)
Journal identifiersISSN: 0143-005X • E-ISSN: 1470-2738
PublisherBMJ (PUBLISHER • GB)
DOI10.1136/jech-2017-209119
PMID28822980
OpenAlexW2747874793
LanguageEN
Citations received7
References cited16

Principal component analysis (PCA) is frequently adopted for creating socioeconomic proxies in order to investigate the independent effects of wealth on disease status. The guidelines and methods for the creation of these proxies are well described and validated. The Demographic and Health Survey, World Health Survey and the Living Standards Measurement Survey are examples of large data sets that use PCA to create wealth indices particularly in low and middle-income countries (LMIC), where quantifying wealth-disease associations is problematic due to the unavailability of reliable income and expenditure data. However, the application of this method to smaller survey data sets, especially in rural LMIC settings, is less rigorously studied. In this paper, we aimed to highlight some of these issues by investigating the association of derived wealth indices using PCA on risk of vector-borne disease infection in Tanzania focusing on malaria and key arboviruses (ie, dengue and chikungunya). We demonstrated that indices consisting of subsets of socioeconomic indicators provided the least methodologically flawed representations of household wealth compared with an index that combined all socioeconomic variables. These results suggest that the choice of the socioeconomic indicators included in a wealth proxy can influence the relative position of households in the overall wealth hierarchy, and subsequently the strength of disease associations. This can, therefore, influence future resource planning activities and should be considered among investigators who use a PCA-derived wealth index based on community-level survey data to influence programme or policy decisions in rural LMIC settings

Economics · Environmental health · Malaria · Population · Socioeconomic status · Socioeconomics · Tanzania · COVID-19 epidemiological studies · Global Health and Epidemiology · Medicine · Mosquito-borne diseases and control

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Unique citing works7
Citations per year1
Citation span2019 - 2026 (8)
Citation velocitycurrent
Highly citedNo
Citation typesNeutral: 5

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