Baseline and longitudinal change in blood pressure and mortality in a Chinese cohort

Bibliographic Data

ID11174449
AuthorsJianbing Wang (0000-0002-5571-2174, Zhejiang University), Jian-Bing Wang (Zhejiang University), Qiu-Chi Huang (Zhejiang University), Shu-Chang Hu (Zhejiang University), Pei-Wen Zheng, Peng Shen (0000-0002-0176-127X, Department of Chronic Disease and Health Promotion, Yinzhou District Center for Disease Control and Prevention, Ningbo, China), Die Li (0000-0001-8801-3671, Zhejiang University), Huai-Chu Lu (Department of Chronic Disease and Health Promotion, Yinzhou District Center for Disease Control and Prevention, Ningbo, China), Xiang Gao (0000-0001-6812-8156, Department of Nutritional Sciences, The Pennsylvania State University, Philadelphia, Pennsylvania, USA), Hong-Bo Lin (Department of Chronic Disease and Health Promotion, Yinzhou District Center for Disease Control and Prevention, Ningbo, China), Kun Chen (0000-0003-3579-5467, Zhejiang University, corresponding author)
Year2018
Volume72
Issue12
Pages1083-1090
Publication date2018-12-01
Open AccessNo
TypeARTICLE
VenueJournal of Epidemiology and Community Health (JOURNAL)
Journal identifiersISSN: 0143-005X • E-ISSN: 1470-2738
PublisherBMJ (PUBLISHER • GB)
DOI10.1136/jech-2018-211050
PMID30077965
OpenAlexW2886723543
LanguageEN
Citations received2
References cited38

BACKGROUND: A J-curve association has been demonstrated for blood pressure (BP) and all-cause mortality, but data on longitudinal change of BP and mortality in Chinese population are limited. METHODS: We performed a retrospective cohort study to examine the association between BP (at baseline and longitudinal change) and risk of mortality in Yinzhou District, Ningbo, China, based on the Yinzhou Health Information System. At baseline, a total of 181 352 subjects aged over 18 years with at least one BP examination record were recruited through the Yinzhou Health Information System. The final analysis was restricted to 168 061 participants after exclusion of outliers of BP. RESULTS: A U-shaped association was observed for BP at baseline and risk of total and cardiovascular mortality. When compared with normotensive participants, patients with hypotension (HRs=1.51, 95% CI 1.21 to 1.88) and stage 3 hypertension (1.28, 95% CI 1.09 to 1.50) had an increased risk of all-cause mortality. Relative to stable BP of normotension, having a rise in BP from normotension to hypertension or from prehypertension to hypertension both conferred an increased risk of total and cardiovascular mortality (total: 1.39 (95% 1.10 to 1.75) and 1.40 (95% 1.15 to 1.69); cardiovascular: 2.22 (95% CI 1.35 to 3.65) and 1.89 (95% CI 1.20 to 2.96), respectively). CONCLUSIONS: Our findings emphasise that hypotension and stage 3 hypertension were associated with an increased risk of all-cause mortality. Longitudinal change from normotensive or prehypertensive levels to 140/90 mm Hg or higher could increase the risk of total and cardiovascular mortality

Blood pressure · Cohort · Cohort study · Environmental health · Longitudinal study · Pathology · Population · Prehypertension · Retrospective cohort study · Risk of mortality · Blood Pressure and Hypertension Studies · Demography · Heart rate and cardiovascular health · Internal Medicine · Medicine · Sodium Intake and Health