P2-268 Risk of cardiovascular disease in diabetics with symptoms of cardiac ischaemia in western region of Nepal

Background The cardiovascular (CV) risk in patients with diabetes is estimated to be two or three times higher than in the non-diabetic population. The prognosis of patients with diabetes following myocardial infarction (MI) remains poorer in comparison with non-diabetics. Objective To find out the relationship between Diabetes and MI in patients with symptoms of cardiac ischaemia. Materials and Methods It was a retrospective study carried out from the data maintained in the Department of Biochemistry of the Manipal Teaching Hospital, Pokhara, Nepal between 1 January 2008 and 1 January 2009. Data of 422 patients with symptoms of cardiac ischaemia who underwent both Troponin and lipid profiles tests were collected. Descriptive statistics and testing of hypothesis were used for the analysis using SPSS V. 16 software. Result Of the 422 subjects, 10.4% were Troponin positive, 62.1% Diabetic, 51.4% greater than 60 year old. Average age of Troponin positive was 67.2 and negative was 58.3 years. A relationship was found to exist between Diabetes and MI (OR=15, p<0.0001), especially in age group greater than 60 year old (OR=10, p<0.0001). Conclusion CV risk should be assessed in all patients with diabetes. Those with a high risk should be treated intensively, and this needs to be clearly explained by their doctors in order to improve compliance

Cardiology · Diabetes mellitus · Disease · Environmental health · Myocardial infarction · Population · Retrospective cohort study · Troponin · Cardiovascular Function and Risk Factors · Endocrinology · Internal Medicine · Medicine