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Impact of prenatal diagnosis by ultrasound on the prevalence of congenital anomalies at birth in southern France

Bibliographic Data

ID11176969
AuthorsClaire Julian‐reynier (Inserm), C Julian-Reynier, N Philip (Inserm), C Scheiner (Inserm), Y Aurran (Inserm), F Chabal (Inserm), A Maron (0000-0001-9431-0808, Inserm), A Gombert (Inserm), Ségolène Aymé (Inserm)
Year1994
Volume48
Issue3
Pages290-296
Publication date1994-06-01
Open AccessNo
TypeARTICLE
VenueJournal of Epidemiology and Community Health (JOURNAL)
Journal identifiersISSN: 0143-005X • E-ISSN: 1470-2738
PublisherBMJ (PUBLISHER • GB)
DOI10.1136/jech.48.3.290
PMID8051530
OpenAlexW2089323721
LanguageEN
Citations received3
References cited11

STUDY OBJECTIVE--The aims were (1) to assess whether termination of pregnancy after prenatal screening by ultrasound affected the prevalence of congenital anomalies at birth, and (2) to examine the trend of this pattern over time. DESIGN--This study deals with congenital anomalies, possibly detectable prenatally or at birth, which were classified as isolated and multiple anomalies; chromosomal anomalies were not included. The prevalence rates of congenital anomalies at birth were determined from case registration data in the Marseille district, France, from the registry of congenital malformations (Eurocat no 22), which covers 23,500 births a year. The chi 2 test for homogeneity in proportions was used to test whether the differences in the total prevalence rates were significant over time. SETTING--The population was defined as all children born to parents living in the Marseille district between January 1 1984 and December 31 1990. PATIENTS--Among the 164,509 pregnancy outcomes monitored during the study, 1795 children with a single congenital anomaly and 288 with multiple congenital anomalies detectable at birth were assessed. MEASUREMENTS AND MAIN RESULTS--The percentage of pregnancy terminations was higher in the case of multiple anomalies (16%) than with single ones (7.5%). Leaving aside the lethal birth defects, this percentage became 7.9% in the case of multiple anomalies and 4.3% with isolated ones. A significant increase (p

Fetus · Obstetrics · Pregnancy · Prenatal diagnosis · Prenatal ultrasound · Radiology · Ultrasound · Ectopic Pregnancy Diagnosis and Management · Medicine · Prenatal Screening and Diagnostics · Ultrasound and Hyperthermia Applications · Pediatrics

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Citations per year0.11
Citation span1998 - 2016 (19)
Highly citedNo

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