Gender-specific risk factors for incident sarcopenia
8-Year follow-up of the English longitudinal study of ageing
Bibliographic Data
| ID | 11178504 |
|---|---|
| Authors | Lin Yang (0000-0002-1698-6666, Medical University of Vienna, corresponding author), Lee Smith (0000-0002-0556-7335, Anglia Ruskin University), Mark Hamer (0000-0002-8726-7992, Loughborough University) |
| Year | 2019 |
| Volume | 73 |
| Issue | 1 |
| Pages | 86-88 |
| Publication date | 2019-01-01 |
| Open Access | No |
| Type | ARTICLE |
| Venue | Journal of Epidemiology and Community Health (JOURNAL) |
| Journal identifiers | ISSN: 0143-005X • E-ISSN: 1470-2738 |
| Publisher | BMJ (PUBLISHER • GB) |
| DOI | 10.1136/jech-2018-211258 |
| PMID | 30368480 |
| OpenAlex | W2898510867 |
| Language | EN |
| Citations received | 4 |
| References cited | 16 |
BACKGROUND: The aetiology of age-related sarcopenia is not known. OBJECTIVES: To investigate if risk of developing sarcopenia differs by gender and to identify gender-specific risk factors of incident sarcopenia in a large population-based cohort of older English adults. METHODS: The sample (n=3404; age 63.4 (SD 7.7) years; 54.1% women) comprised older community-dwelling adults recruited from the English Longitudinal Study of Ageing. Sarcopenia was defined as handgrip <26 kg in men and <16 kg in women. Handgrip strength was assessed at baseline (2004/2005) and repeated at follow-up (2012/2013). Analysed risk factors included baseline anthropometric measures, smoking, vigorous and moderate physical activity, depressive symptoms, chronic illnesses and wealth. After excluding participants with sarcopenia at baseline, multivariable logistic regressions were used to explore baseline risk factors for incident sarcopenia. RESULTS: During 8-year follow-up, 208 and 287 cases of sarcopenia were identified in men (n=1564) and women (n=1840), respectively. Women were at 20% (age adjusted OR=1.20, 95% CI 0.98 to 1.47) higher risk of developing sarcopenia than men. The inverse association between physical activity and sarcopenia risk was observed at moderate (OR=0.44, 95% CI 0.27 to 0.67) and vigorous (0.53, 95% CI 0.31 to 0.82) intensities in men and only vigorous (OR=0.44, 95% CI 0.28 to 0.68) intensity in women. Social factors, such as wealth, and chronic health conditions appeared to be more strongly associated with sarcopenia in men. CONCLUSION: Women are at higher risk of developing incident sarcopenia than men, and this is likely explained by a range of gender-specific risk factors
Ageing · Anthropometry · Cohort · Cohort study · Environmental health · Longitudinal study · Odds ratio · Physical therapy · Population · Prospective cohort study · Risk factor · Sarcopenia · Body Composition Measurement Techniques · Demography · Frailty in Older Adults · Internal Medicine · Medicine · Nutrition and Health in Aging · Gerontology
Gender-Specific Risk Factors and Prevalence for Sarcopenia among Community-Dwelling Young-Old Adults
Sex Differences of Sarcopenia in an Elderly Asian Population
Effects of resistance training on muscle mass, strength, and physical function in older women with sarcopenia
Habitual physical activity and sarcopenia
| Citations per year | 1 |
|---|---|
| Citation span | 2022 - 2026 (5) |
| Highly cited | No |