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Trajectories of alcohol consumption up to 30 years before and after the diagnosis of cardiovascular diseases

A longitudinal case–control study of 12 502 participants

Bibliographic Data

ID11180329
AuthorsChengyi Ding (0000-0001-7959-366X, The London College, corresponding author), Dara O'Neill, Darragh O’Neill (0000-0002-8830-0264, University College London), Amelia Britton (0000-0002-6412-5430, University College London), Annie Britton
Year2022
Volume76
Issue5
Pages497-504
Publication date2022-05-01
Open AccessNo
TypeARTICLE
VenueJournal of Epidemiology and Community Health (JOURNAL)
Journal identifiersISSN: 0143-005X • E-ISSN: 1470-2738
PublisherBMJ (PUBLISHER • GB)
DOI10.1136/jech-2021-217237
PMID34965970
OpenAlexW4200460855
LanguageEN
References cited34

BACKGROUND: To examine the longitudinal trajectories of alcohol consumption prior to and following the diagnosis of cardiovascular diseases (CVD). METHODS: We conducted a case-control study of 2501 incident cases of angina, myocardial infarction or stroke and 10 001 matched controls without the condition. Repeated measures of alcohol were centred on the date of diagnosis, spanning up to 30 years before and after CVD onset. Mean trajectories of weekly consumption were estimated using growth curve models. RESULTS: For trajectories prior to diagnosis, mean volume of alcohol consumed among male cases increased over time, peaking at around 8 years before diagnosis at 95 (95% CI 60 to 130) g/week and declining afterwards. Trajectories following diagnosis showed mean consumption in male cases dropped from 87 (95% CI 54 to 120) g/week to 74 (95% CI 45 to 102) g/week after the date of diagnosis and then slightly rose to 78 (95% CI 40 to 116) g/week at the subsequent 3.5 years, before gradually declining to 31 (95% CI 2 to 61) g/week at 30 years after diagnosis. Mean consumption among female cases remained stable prior to diagnosis (at about 30 g/week), fell marginally to 25 (95% CI 20 to 30) g/week after the date of diagnosis and kept decreasing afterwards. Similar trajectories were obtained in cases and controls. CONCLUSIONS: This is the first attempt to show how patients with CVD change their drinking volume over such a wide time span. Future research needs to establish insight into drinking behaviour in other ways (such as frequency and context) and address the impact of changes in drinking on patients with CVD

Alcohol · Alcohol consumption · Angina · Incidence (geometry) · Longitudinal study · Myocardial infarction · Pathology · Stroke (engine) · Alcohol Consumption and Health Effects · Alcoholism and Thiamine Deficiency · Demography · Internal Medicine · Medicine · Substance Abuse Treatment and Outcomes · Surgery · Pediatrics

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Highly citedNo

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