Reliability of data from proxy respondents in an international case-control study of cardiovascular disease and oral contraceptives. World Health Organization Collaborative Study of Cardiovascular Disease and Steroid Hormone Contraception
Bibliographic Data
| ID | 11180813 |
|---|---|
| Authors | N Poulter (University College London), N R Poulter, Choon Lan Chang (University College London), T M Farley, Tim Farley (University College London), Michael Marmot (0000-0002-2431-6419, University College London), M G Marmot |
| Year | 1996 |
| Volume | 50 |
| Issue | 6 |
| Pages | 674-680 |
| Publication date | 1996-12-01 |
| Open Access | No |
| Type | ARTICLE |
| Venue | Journal of Epidemiology and Community Health (JOURNAL) |
| Journal identifiers | ISSN: 0143-005X • E-ISSN: 1470-2738 |
| Publisher | BMJ (PUBLISHER • GB) |
| DOI | 10.1136/jech.50.6.674 |
| PMID | 9039388 |
| OpenAlex | W2169160283 |
| Language | EN |
| Citations received | 5 |
| References cited | 11 |
STUDY OBJECTIVES: To evaluate the reliability of data supplied in a case-control study by proxy respondents for cases who were too ill to do so themselves. DESIGN: A hospital based, case-control study of the current use of oral contraceptives (OC) and cardiovascular diseases. Data from "true" controls matched to a subset of cases were compared with those supplied by proxy respondents about the true controls. SETTING: Hospitals in 21 centres from Africa, Asia, Europe, and Latin America. PATIENTS AND PARTICIPANTS: For a subset of cases, 403 pairs of controls-one "true" and one proxy-were interviewed. "True" controls were matched by age, place, and time of admission and were admitted with 1 of 27 permissible diagnoses not associated with OC use. Proxy controls were either relatives or friends of true controls. MAIN RESULTS: Levels of concordance between data from proxy and true controls were high for most variables regarding recent events, including current OC use, but were greatly diminished when detailed information, particularly from the past, was required. Husbands were usually the best proxy, although this was question-specific. The sensitivity and specificity of proxy responses were 93% (95% confidence intervals: 77%, 99%) and 100% (98%, 100%) respectively, for current use of OC. Assuming the misclassification of current OC use by proxy cases is similar to that produced by proxy controls, the estimated impact of using proxy data on risk estimates associated with current OC use was to bias the overall estimate of risk of stroke by less than 3% and the risks of both acute myocardial infarction and venous thromboembolism by less than 1%. CONCLUSIONS: Friends or relatives, and particularly husbands, provided reliable information when used as proxy respondents for young women. The estimated impact of misclassification by proxy respondents on overall risk estimates in the WHO collaborative study was less than that which would have arisen if information from proxy respondents had not been used
Case-control study · Concordance · Confidence interval · Disease · Proxy (statistics) · Statistics · Demography · Global Maternal and Child Health · Internal Medicine · Medicine · Pharmacovigilance and Adverse Drug Reactions · Reproductive Health and Contraception
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Completeness and Utility of Interview Data from Proxy Respondents in Prenatal Care Research in Rural China
Combined oral contraceptives, smoking, and cardiovascular risk
The evaluation of agreement on continuous variables by the intraclass correlation coefficient
Influence of proxy respondents in children's health interview surveys
| Citations per year | 0.17 |
|---|---|
| Citation span | 1997 - 2011 (15) |
| Highly cited | No |