Pular para o conteúdo principal

ETHNOS_APP

Início • Busca • Periódicos • Lista 0

The Role of Despair in Predicting Self-Destructive Behaviors

Dados Bibliográficos

ID11290455
AutoresL Gaydosh (0000-0002-0036-626X, University of North Carolina at Chapel Hill, autor correspondente), Audrey Kelly, Audrey L Kelly (0000-0003-1783-7678, University of North Carolina at Chapel Hill), Iliya Gutin (0000-0003-4216-8963, Syracuse University), Lilly Shanahan (0000-0002-4534-6924, Youth Development), Jennifer Godwin (0000-0001-5258-1351, Center for Child and Family Health), Kathleen Mullan Harris (0000-0001-9757-1026, University of North Carolina at Chapel Hill), William Copeland (0000-0002-1348-7781, University of Vermont)
Ano2025
Volume44
Fascículo3
Páginas33-33
Data de publicação2025-06-01
Peer ReviewedSim
Open AccessSim
TipoARTICLE
PeriódicoPopulation Research and Policy Review (JOURNAL)
Identificadores do periódicoISSN: 0167-5923 • E-ISSN: 1573-7829
EditoraSpringer Science and Business Media LLC (PUBLISHER)
DOI10.1007/s11113-025-09952-4
PMID40376253
OpenAlexW4410322491
IdiomaEN
Citações recebidas1
Referências citadas65

Working age (25-64) mortality in the US has been increasing for decades, driven in part by rising deaths due to drug overdose, as well as increases in suicide and alcohol-related mortality. These deaths have been hypothesized by some to be due to despair, but this has rarely been empirically tested. For despair to explain mortality due to alcohol-related liver disease, suicide, and drug overdose, it must first predict the behaviors that lead to such causes of death. To that end, we aim to answer two research questions. First, does despair predict the behaviors that are antecedent to the "deaths of despair"? Second, what measures and domains of despair are most important? We use data from over 6000 individuals at five waves of the National Longitudinal Study of Adolescent to Adult Health and apply supervised machine learning to assess the role of despair in predicting self-destructive behaviors associated with these causes of death. Comparing predictive performance within each outcome using measures of despair to benchmark models of clinical and prior behavioral predictors, we evaluate the added predictive value of despair above and beyond established risk factors. We find that despair underperforms compared to clinical risk factors for suicidal ideation and heavy drinking, but over performs compared to clinical risk factors and prior behaviors for illegal drug use and prescription drug misuse. We also compare model performance and feature importance across outcomes; our ability to predict thoughts of suicide, drug abuse and misuse, and heavy drinking differs depending on the behavior, and the relative importance of different indicators of despair varies across outcomes as well. Our findings suggest that the self-destructive behaviors are distinct and the pathways from despair to self-destructive behavior varied. The results draw into question the relevance of despair as a unifying framework for understanding the current crisis in midlife health and mortality

Mental Health Research Topics · Mental Health Treatment and Access · Psychology · Suicide and Self-Harm Studies

  • They Not Like Us

    Open Access•Pamela Jackson, Pamela Braboy Jackson•Journal of Health and Social…•2026

  • Self-medication with alcohol or drugs for mood and anxiety disorders

    Open Access•Sarah Turner, Natalie Mota et al.•Depression and Anxiety•2018

  • Receiver Operating Characteristic Curve in Diagnostic Test Assessment

    Open Access•Jayawant N Mandrekar•Journal of Thoracic Oncology•2010

  • The drug abuse screening test

    Open Access•Harvey A Skinner•Addictive Behaviors•1982

  • Mortality and Morbidity in the 21st Century

    Anne Case, Angus Deaton•Brookings Papers on Economic…•2017

  • Cohort Profile

    Open Access•Kathleen Mullan Harris, Carolyn T Halpern et al.•International Journal of…•2019

  • Association Between Educational Attainment and Causes of Death Among White and Black US Adults, 2010-2017

    I Sasson, M D Hayward•JAMA•2019

  • A comprehensive review of the psychometric properties of the Drug Abuse Screening Test

    Open Access•Errol Yudko, Olga Lozhkina et al.•Journal of Substance Abuse…•2007

  • Life Expectancy and Mortality Rates in the United States, 1959-2017

    Steven H Woolf, Heidi Schoomaker•JAMA•2019

  • Suicide, Suicide Attempts, and Suicidal Ideation

    E David Klonsky, Alexis May et al.•Annual Review of Clinical…•2016

  • Random Forests

    Open Access•Leo Breiman•Machine Learning•2001

  • Rising morbidity and mortality in midlife among white non-Hispanic Americans in the 21st century

    Open Access•Anne Case, Angus Deaton•Proceedings of the National…•2015

  • Trends in Binge and Heavy Drinking among Adults in the United States, 2011–2017

    Open Access•Sunday Azagba, Lingpeng Shan et al.•Substance Use & Misuse•2020

  • Visualizing Age, Period, and Cohort Patterns of Substance Use in the U.S. Opioid Crisis

    Open Access•A M Verdery, Kira England et al.•Socius Sociological Research for…•2020

  • Deaths of Despair and the Future of Capitalism

    Anne Case, Angus Deaton•Deaths of Despair and the Future…•2020

  • Mortality from Suicide, Chronic Liver Disease, and Drug Poisonings among Middle-Aged U.S. White Men and Women, 1980–2013

    Ryan K Masters, Andrea M Tilstra et al.•Biodemography and Social Biology•2017

  • Growing sense of social status threat and concomitant deaths of despair among whites

    Open Access•Arjumand Siddiqi, Odmaa Sod-Erdene et al.•SSM - Population Health•2019

  • Drug and Alcohol Abuse

    Dana A Glei, M Weinstein•American Journal of Health Behavior•2019

  • Opioid-related mortality in rural America

    Open Access•Khary K Riggs, Khary K Rigg et al.•International Journal of Drug…•2018

  • More than a rural revolt

    Open Access•M Monnat, David L Brown•Journal of Rural Studies•2017

  • Trends in Mortality Risk by Education Level and Cause of Death Among US White Women From 1986 to 2006

    J K Montez, A Zajacova•American Journal of Public Health•2013

  • Despair as a Cause of Death

    Ana V Diez Roux•American Journal of Public Health•2017

  • The Depths of Despair Among US Adults Entering Midlife

    L Gaydosh, R A Hummer et al.•American Journal of Public Health•2019

  • Does Despair Really Kill? A Roadmap for an Evidence-Based Answer

    Lilly Shanahan, Sherika N Hill et al.•American Journal of Public Health•2019

  • Research Note

    Open Access•Iliya Gutin, L Gaydosh•Demography•2025

  • Trends in Life Expectancy and Lifespan Variation by Educational Attainment

    Open Access•I Sasson•Demography•2016

  • Demographic and Geographic Variation in Fatal Drug Overdoses in the United States, 1999–2020

    Open Access•M Monnat, Shannon M Monnat•The Annals of the American…•2022

  • US Mortality in an International Context

    Open Access•Jessica Y Ho, H Preston et al.•Population and Development Review•2010

  • Are employment and social integration more strongly associated with deaths of despair than psychological or economic distress

    Open Access•Dana A Glei, Chioun Lee et al.•Social Science & Medicine•2024

  • Defining despair

    Open Access•Iliya Gutin, William Copeland et al.•Social Science & Medicine•2023

  • Understanding the health decline of Americans in boomers to millennials

    Open Access•H Zheng, Jonathan Dirlam et al.•Social Science & Medicine•2023

  • Changes in mental health, pain, and drug misuse since the mid-1990s

    Open Access•Dana A Glei, Andrew Stokes et al.•Social Science & Medicine•2020

  • Perception has its Own Reality

    Open Access•Dana A Glei, N Goldman et al.•Population and Development Review•2018

  • The Contemporary American Drug Overdose Epidemic in International Perspective

    Open Access•Jessica Y Ho•Population and Development Review•2019

  • Deaths of Despair in Comparative Perspective

    Lawrence King, Gábor Scheiring et al.•Annual Review of Sociology•2022

Obras citantes distintas1
Citações por ano1
Intervalo de citações2026 - 2026 (1)
Velocidade de citaçãocurrent
Altamente citadoNão
Ethnos_APP • Projeto Open Source • Licença MIT • Frontend v2.0.0 • Privacidade e Cookies • Documentação da API: api.ethnos.app/docs • Código da API: GitHub • DOI: 10.5281/zenodo.17049435 • Código do Frontend: GitHub • DOI: 10.5281/zenodo.17050053 • cruz.rio.br • Expectantes Misericordiae