Prenatal sex hormones and human aggression

We review data on aggression from psychological studies of offspring from two categories of abnormal prenatal sex hormone conditions: 1) endocrine disorders, and 2) hormone treatment during pregnancy. Both sources yield trends and some significant findings that are in line with the animal research based expectations of a positive androgen effect on the development of aggressive behavior. However, the available studies have many methodological weaknesses, and the results are not strong and open to interpretations by factors other than prenatal hormones. Potential modes of prenatal sex hormone effects are also discussed. In the second part, we present data on 13 boys and 15 girls who had been exposed to medroxyprogesterone acetate (MPA) in utero and on 28 closely pair-matched controls. The double-blind follow-up examination at age 9 to 14 years included questionnaires, half-structured interviews with mother and child separately, and a battery of psychological tests. Interviews were tape-recorded and rated by two independent raters. The results show weak but consistent differences, with the MPA-exposed subjects being lower in self- or mother-reported aggression than the controls. The results cannot be accounted for by differences in aggression-related rearing styles. However, the influence of pregnancy pathology cannot be totally excluded. We conclude that the available data are compatible with the hypothesis that prenatal sex hormones influence the development of human aggressive behavior. More sophisticated research studies are needed, however, to demonstrate hormonal effects and their mechanism of action in a reliable and valid fashion

Aggression · Developmental psychology · Digit ratio · Hormone · Medical emergency · Medroxyprogesterone acetate · Offspring · Poison control · Pregnancy · Testosterone (patch · Adolescent Sexual and Reproductive Health · Clinical Psychology · Endocrinology · Gender Roles and Identity Studies · Medicine · Physiology · Psychology · Sexual Differentiation and Disorders

• Human behavioral sex differences

  Marcia L Collaer, Melissa Hines et al.•Psychological Bulletin•1995

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• Sexual orientation after prenatal exposure to exogenous estrogen

  Open Access•Anke A Ehrhardt, Anke Α Ehrhardt et al.•Archives of Sexual Behavior•1985

  Añadir item

• Sex-dimorphic behavior in childhood subsequent to prenatal exposure to exogenous progestogens and estrogens

  Open Access•Anke A Ehrhardt, Anke Α Ehrhardt et al.•Archives of Sexual Behavior•1984

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• Sex differences in human mortality

  Open Access•Ingrid Waldron•Social Science & Medicine•1983

  Añadir item

• A Cross-Cultural Analysis of Sex Differences in the Behavior of Children Aged Three Through 11

  Beatrice B Whiting, Beatrice Whiting et al.•The Journal of Social Psychology•1973

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• Are women always less aggressive than men? A review of the experimental literature

  Ann Frodi, Jacqueline Macaulay et al.•Psychological Bulletin•1977

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• Effects of Neonatal Cyproterone Acetate Administration on Isolation-Induced Fighting Behavior and Mounting Behavior in Male and Female to Strain Albino Mice

  Open Access•Angela E Poole, Paul F Brain•Aggressive Behavior•1975

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• Fetal androgens in the early treated adrenogenital syndrome of 46 XX hermaphroditism

  Open Access•John Money, Mark Schwartz et al.•Aggressive Behavior•1976

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• Progestin‐induced hermaphroditism

  Anke A Ehrhardt, Anke Α Ehrhardt et al.•The Journal of Sex Research•1967

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• The Distribution of Personality Traits in Seven‐year‐old Children

  Open Access•MAY A DAVIDSON, R G McINNES et al.•British Journal of Educational…•1957

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• Neuroendocrinology

  Open Access•Robert W Goy, David A Goldfoot•Archives of Sexual Behavior•1975

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• Behavioral sexology

  Open Access•John Money, Charles Ogunro•Archives of Sexual Behavior•1974

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• Prenatal exposure to synthetic progestins and estrogens

  Open Access•June Machover Reinisch, William G Karow•Archives of Sexual Behavior•1977

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