Incorporating Gender and Sex Dimensions in Medical Research

Bibliographic Data

ID11935282
AuthorsAnita Holdcroft (Imperial College London, corresponding author), Saowarat Snidvongs (0000-0001-9952-3685, Barts and The London NHS Trust, UK, corresponding author), Karen J Berkley (Florida State University, corresponding author)
Year2011
Volume36
Issue2
Pages180-192
Publication date2011-06-01
Open AccessYes
TypeARTICLE
VenueInterdisciplinary Science Reviews (JOURNAL)
Journal identifiersISSN: 0308-0188 • E-ISSN: 1743-2790
PublisherTaylor & Francis (PUBLISHER • GB)
DOI10.1179/030801811x13013181961590
OpenAlexW1966226589
LanguageEN
Citations received2
References cited30

Sex differences have been ascribed mainly to hormonal and life-span factors, while neglecting chromosomal and socio-cultural determinants. Science is now reviewing the disregard for sex and gender as a potential explanation for the lack of expected outcomes in whole populations from clinical research. The medical research process begins with a hypothesis that is applied, generating results that can be disseminated. Many factors impact on this process that can be ascribed to sex, as a biological construct, and gender, as a psychosocial process involving experimental subjects, research- ers, funders and the public. Drug trial data analysis and publication of data from women and men have recently been scrutinized and found lacking, because expected clinical outcomes from ‘evidence-based’ guidelines are not being achieved. Hence visibility of sex and gender in all aspects of medical research is considered essential if personalized therapies are to bring benefits to both men and women

Biological sex · Clinical trial · Construct (python library · Medical research · Process (computing · Psychosocial · Psychotherapist · Transgender · Visibility · Computer Science · Diversity and Career in Medicine · Health Systems, Economic Evaluations, Quality of Life · Medicine · Psychology · Sex and Gender in Healthcare · Social Psychology

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