Stress and physiology in clinical research with risk-exposed children
From mechanism to application
Bibliographic Data
| ID | 11941362 |
|---|---|
| Authors | Thomas G O’connor (0009-0000-4894-9002, University of Rochester Medicine, corresponding author), Ana Vallejo Sefair (0000-0003-2900-4120, University of Rochester) |
| Year | 2019 |
| Volume | 43 |
| Issue | 3 |
| Pages | 340-350 |
| Publication date | 2019-09-26 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Adoption & Fostering (JOURNAL) |
| Journal identifiers | ISSN: 0308-5759 • E-ISSN: 1740-469X |
| Publisher | SAGE Publishing (PUBLISHER • US) |
| DOI | 10.1177/0308575919856162 |
| OpenAlex | W2976776420 |
| Language | EN |
| Citations received | 1 |
| References cited | 43 |
Research findings from diverse studies converge in suggesting that the experience of early severe and protracted stress is associated with a wide range of behavioural and physical health problems. The public health and clinical implications of these findings are substantial, but their successful applications to improve child health have been limited. What is clear is that this successful application depends, at least in part, on a clear understanding of the mechanisms involved. The current review considers the likely role of stress physiology and the Hypothalamic-Pituitary-Adrenal (HPA) axis, one dominant model for explaining how early stress exposures may have lasting effects on mental and physical health. In addition to highlighting illustrative findings, we consider the practical barriers and challenges for increasing the presence of biological markers in clinical research
Child health · Developmental psychology · Mechanism (biology · Mental health · Pathology · Physical health · Psychiatry · Public health · Stress (linguistics · Child and Adolescent Psychosocial and Emotional Development · Clinical Psychology · Early Childhood Education and Development · Medicine · Psychology · Stress Responses and Cortisol · Pediatrics
Pituitary-Adrenal and Autonomic Responses to Stress in Women After Sexual and Physical Abuse in Childhood
The origins of the developmental origins theory
The Neurobiology of Stress and Development
The ‘Trier Social Stress Test’ – A Tool for Investigating Psychobiological Stress Responses in a Laboratory Setting
Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults
Biobehavioral Organization in Securely and Insecurely Attached Infants
Cumulative Childhood Stress and Autoimmune Diseases in Adults
Cardiovascular and Cortisol Reactions to Acute Psychological Stress and Adiposity
Multidimensional Treatment Foster Care
Developing Evidence‐Based Interventions for Foster Children
| Citations per year | 0.2 |
|---|---|
| Citation span | 2021 - 2021 (1) |
| Highly cited | No |