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Frequency and non random distribution of silver-staining NORs on acrocentric chromosomes from neonate and adult human lymphocytes

Bibliographic Data

ID12030532
AuthorsL Lamberti (University of Turin, corresponding author), Paola Bigatti (University of Turin), G Ardito (University of Florence)
Year1991
Volume6
Issue2
Pages153-157
Publication date1991-06-01
Open AccessYes
TypeARTICLE
VenueInternational Journal of Anthropology (JOURNAL)
Journal identifiersISSN: 0393-9383 • E-ISSN: 1824-3096
PublisherSpringer Nature (PUBLISHER • SG)
DOI10.1007/bf02443949
OpenAlexW2087195872
LanguageEN
References cited16

The NORs frequency in a group of newborns and adults was determined by the gelatine silver staining technique. A higher number of Ag-NORs (χ2 test, p<0.01) was found in adults than in newborns. The lack of correlation between cell proliferating rate index (PRI) and frequency of Ag-NORs let us suppose that the decrease of Ag-positive NORs in neonates could probably be due to factors different from cell kinetics. A non random distribution of Ag-NORs on the acrocentric chromosomes was also demonstrated: chromosome 21, in particular, showed the highest frequency, while chromosome 15, the lowest

Andrology · Biology · Centromere · Chromosome · Gene · Nucleolus organizer region · Silver stain · Staining · Advanced biosensing and bioanalysis techniques · Chromosomal and Genetic Variations · Medicine · RNA and protein synthesis mechanisms · Genetics · Molecular Biology

Highly citedNo

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