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Recent advances in gene therapy with skin cells

Bibliographic Data

ID12417718
AuthorsMarcela Del Río (0000-0003-2910-7189, Fundación Botín, corresponding author), Fernando Larcher (0000-0002-6771-3561, Fundación Botín), José L Jorcano (0000-0002-9762-5992, Fundación Botín)
Year2002
Volume10
Issue3
Pages369-388
Publication date2002-07-01
Open AccessYes
TypeARTICLE
VenueEuropean Review (JOURNAL)
Journal identifiersISSN: 1062-7987 • E-ISSN: 1474-0575
PublisherCambridge University Press (CUP) (PUBLISHER)
DOI10.1017/s1062798702000297
OpenAlexW2084426711
LanguageEN

Somatic gene therapy remains a promising therapeutic approach for both inherited and acquired disorders. Among the tissues amenable to gene therapy, the skin, and particularly the epidermal cells, present several features advantageous for genetic manipulation and monitoring of therapeutic effects. Candidate diseases for cutaneous gene therapy not only involve skin defects but also systemic abnormalities. The robust basic and pre-clinical data gathered during the last few years have allowed the imminent launching of keratinocyte-based gene therapy with applications to patients

Bioinformatics · Biology · Computational biology · Gene · Genetic enhancement · Somatic cell · Medicine · Pluripotent Stem Cells Research · RNA Interference and Gene Delivery · Virus-based gene therapy research · Genetics

Highly citedNo

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