Psychological Distress and Alzheimer’s Disease Mortality in the United States
Results from the 1997–2014 National Health Interview Survey-National Death Index Record Linkage Study
Bibliographic Data
| ID | 12797151 |
|---|---|
| Authors | Gopal K Singh (0000-0002-7820-0323, Office of Health Equity, Health Resources and Services Administration, Rockville, MD, USA, corresponding author), Hyunjung Lee (0000-0003-0783-5484, Office of Health Equity, Health Resources and Services Administration, Rockville, MD, USA) |
| Year | 2020 |
| Volume | 33 |
| Issue | 3-4 |
| Pages | 260-272 |
| Publication date | 2020-12-04 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Journal of Aging and Health (JOURNAL) |
| Journal identifiers | ISSN: 1552-6887 • E-ISSN: 0898-2643 |
| Publisher | SAGE Publishing (PUBLISHER • US) |
| DOI | 10.1177/0898264320977309 |
| PMID | 33275069 |
| OpenAlex | W3109096122 |
| Language | EN |
| Citations received | 1 |
| References cited | 31 |
Objective: This study examines the association between psychological distress and Alzheimer's disease mortality among US adults aged ≥45. Methods: We analyzed the Kessler 6-item psychological distress scale as a risk factor for Alzheimer's mortality using the pooled 1997-2014 National Health Interview Survey (NHIS)- National Death Index (NDI) database ( N = 265,089). Cox regression was used to model mortality as a function of psychological distress and sociodemographic and behavioral covariates. Results: The Alzheimer's mortality risk was 97% higher (HR = 1.97; 95% confidence interval [CI] = 1.37, 2.84) in adults with serious psychological distress compared with those without psychological distress, controlling for sociodemographic covariates. The relative mortality risk remained statistically significant (HR = 1.49; 95% CI = 1.04, 2.13) after additional adjustment for smoking, alcohol consumption, health status, activity limitation, and body mass index. Discussion: US adults had significantly higher risks of Alzheimer's disease mortality at higher psychological distress levels. These findings underscore the significance of addressing psychological well-being as a strategy for reducing Alzheimer's disease mortality
Alzheimer's disease · Body mass index · Confidence interval · Disease · Distress · Environmental health · Hazard ratio · Mental health · National Death Index · National Health Interview Survey · Population · Proportional hazards model · Psychiatry · Psychological distress · Clinical Psychology · Dementia and Cognitive Impairment Research · Demography · Health disparities and outcomes · Health, psychology, and well-being · Medicine · Psychology · Gerontology · Internal Medicine
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| Citations per year | 0.5 |
|---|---|
| Citation span | 2024 - 2024 (1) |
| Highly cited | No |