Increased Odds of Incident Alzheimer’s Disease and Related Dementias in Presence of Common Non-Cancer Chronic Pain Conditions in Appalachian Older Adults
Bibliographic Data
| ID | 12797537 |
|---|---|
| Authors | Sumaira Khalid (0000-0003-2739-0320, West Virginia University, corresponding author), Usha Sambamoorthi (0000-0001-8311-1360, West Virginia University), Amna Umer (0000-0003-2987-7650, West Virginia University), Christa Lilly (0000-0002-0009-0638, West Virginia University), Christa L Lilly (West Virginia University), Diane Gross (West Virginia University), Diane K Gross (West Virginia University), Kim E Innes (0000-0002-6395-7972, West Virginia University) |
| Year | 2021 |
| Volume | 34 |
| Issue | 2 |
| Pages | 158-172 |
| Publication date | 2021-08-05 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Journal of Aging and Health (JOURNAL) |
| Journal identifiers | ISSN: 1552-6887 • E-ISSN: 0898-2643 |
| Publisher | SAGE Publishing (PUBLISHER • US) |
| DOI | 10.1177/08982643211036219 |
| PMID | 34351824 |
| OpenAlex | W3192990066 |
| Language | EN |
| Citations received | 2 |
| References cited | 83 |
In this large cohort of older Appalachian Medicare beneficiaries, baseline NCPCs showed a strong, positive, dose-response relationship to odds for incident ADRD; this association appeared partially mediated by depression and anxiety. Further longitudinal research in this and other high-risk, rural populations are needed to evaluate the causal relation between NCPC and ADRD
Anxiety · Cohort study · Dementia · Depression (economics · Disease · Environmental health · Mood · Odds ratio · Population · Psychiatry · Dementia and Cognitive Impairment Research · Demography · Medicine · Musculoskeletal pain and rehabilitation · Stroke Rehabilitation and Recovery · Gerontology · Internal Medicine
Summary of the evidence on modifiable risk factors for cognitive decline and dementia
A classification of chronic pain for ICD-11
Prevalence of Chronic Pain and High-Impact Chronic Pain Among Adults — United States, 2016
Global, regional, and national burden of Alzheimer's disease and other dementias, 1990–2016
Rural‐Urban Differences in Alzheimer's Disease and Related Disorders Diagnostic Prevalence in Kentucky and West Virginia
High Self‐Reported Prevalence of Diabetes Mellitus, Heart Disease, and Stroke in 11 Counties of Rural Appalachian Ohio
Older Rural‐ and Urban‐Dwelling Appalachian Adults With Mild Cognitive Impairment
Non-Cancer Chronic Pain Conditions and Risk for Incident Alzheimer’s Disease and Related Dementias in Community-Dwelling Older Adults
Pain as a global public health priority
The Impact of Changes in Population Health and Mortality on Future Prevalence of Alzheimer’s Disease and Other Dementias in the United States
| Citations per year | 2 |
|---|---|
| Citation span | 2025 - 2026 (2) |
| Highly cited | No |