The Impact of Late-Life Psychological Disorders on the Risk of Cognitive Impairment
Evidence From a 5-Year Prospective Cohort Study
Bibliographic Data
| ID | 12798356 |
|---|---|
| Authors | Yu‐Kai Lin (0000-0002-2668-9833, University of Taipei, corresponding author), Wan‐Yu Lin (0000-0002-3385-4702, Ministry of Health and Welfare), Wan-Yu Lin (0009-0005-2357-4749, University of Taipei) |
| Year | 2025 |
| Pages | 8982643251391892-8982643251391892 |
| Publication date | 2025-10-25 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Journal of Aging and Health (JOURNAL) |
| Journal identifiers | ISSN: 1552-6887 • E-ISSN: 0898-2643 |
| Publisher | SAGE Publishing (PUBLISHER • US) |
| DOI | 10.1177/08982643251391892 |
| PMID | 41138243 |
| OpenAlex | W4415548317 |
| Language | EN |
| References cited | 74 |
BackgroundPsychological disorders and cognitive impairment frequently co-occur in older adults, posing challenges to healthy aging. This study aimed to examine the association between late-life psychological disorders and the risk of developing cognitive impairment.MethodsProspective study analyzed data from 28,706 older adults enrolled in the Taipei City Older Adults Health Examination (2012-2016), among whom 10.3% developed cognitive impairment during follow-up. Psychological disorders were assessed using the five-item Brief Symptom Rating Scale (BSRS-5), and cognitive impairment was evaluated with the Ascertain Dementia eight-item Questionnaire (AD-8). Cox proportional hazards models were applied to estimate the associations.ResultsPsychological disorder severity exhibited a dose-response relationship with cognitive impairment risk. Compared to participants without disorders, those with mild, moderate, and severe symptoms had 2.47-, 3.99-, and 8.60-fold increased risks of cognitive impairment, respectively.ConclusionEarly identification and targeted interventions for psychological disorders may mitigate the risk of cognitive decline and promote healthy aging
Cognition · Cognitive decline · Cognitive impairment · Cohort study · Dementia · Prospective cohort study · Psychological intervention · Rating scale · Dementia and Cognitive Impairment Research · Health disparities and outcomes · Sleep and related disorders
Perceived social isolation and cognition
Summary of the evidence on modifiable risk factors for cognitive decline and dementia
The Neuroendocrinology of Social Isolation
Loneliness, depression and cognitive function in older U.S. adults
The AD8
Loneliness and depression in the elderly
Dementia prevention, intervention, and care
Gender-and age-specific associations of sleep duration and quality with cognitive impairment in community-dwelling older adults in Anhui Province, China
Social anxiety and loneliness among older adults
Mediators of educational differences in dementia risk later in life
| Highly cited | No |
|---|