Association of Osteoarthritis and Functional Limitations With Cognitive Impairment Among Older Adults in the United States

Bibliographic Data

ID12798453
AuthorsMaxwell J Rakutt (0000-0003-2202-3716, University of Kentucky College of Medicine, Lexington, USA), RYAN A MACE (0000-0001-5738-8606, Department of Psychiatry, Massachusetts General Hospital, Boston, USA), Caitlin Conley (0000-0001-9874-5200, University of Kentucky), Austin V Stone (0000-0002-9406-7884, University of Kentucky), Stephen T Duncan (0000-0002-2849-0326, University of Kentucky), Jonathan Greenberg (0000-0002-4875-2207, Department of Psychiatry, Massachusetts General Hospital, Boston, USA), David C Landy (0000-0002-4024-7679, University of Kentucky), Ana-Maria Vranceanu, Ana‐maria Vranceanu (0000-0003-3994-6488, Department of Psychiatry, Massachusetts General Hospital, Boston, USA), Cale A Jacobs (0000-0002-9300-5550, Massachusetts General Brigham Sports Medicine, Brigham and Women's Hospital, Boston, MA, USA, corresponding author)
Year2023
Volume35
Issue9
Pages643-650
Publication date2023-01-21
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueJournal of Aging and Health (JOURNAL)
Journal identifiersISSN: 1552-6887 • E-ISSN: 0898-2643
PublisherSAGE Publishing (PUBLISHER • US)
DOI10.1177/08982643231153459
PMID36680455
OpenAlexW4317653788
LanguageEN
References cited58

Objective: Given overlapping pathophysiology, this study sought to assess the association between osteoarthritis (OA), functional impairment, and cognitive impairment in the aging population. Methods: The National Health and Nutrition Examination Survey was used to identify participants >60 years of age. We analyzed multivariable associations of grouped participants that underwent cognitive function testing using linear and logistic regression, adjusting for sex, age, race, and ethnicity. Results: Of 2776 identified participants representing a population of 50,242,917, 40% did not report OA or functional limitations; 21% had OA but not functional limitations; 15% did not have OA but had functional limitations; 17% had OA and related functional limitations; and 7% had OA and non-arthritic functional limitations. OA was not independently associated with cognitive impairment. Contrarily, functional limitations were associated with cognitive impairment regardless of OA diagnosis. Discussion: Cognitive impairment is not associated with OA, but rather functional limitations, potentially guiding future intervention

Association (psychology · Cognition · Cognitive impairment · Functional impairment · Logistic regression · Physical therapy · Population · Psychiatry · Clinical Psychology · Fibromyalgia and Chronic Fatigue Syndrome Research · Medicine · Osteoarthritis Treatment and Mechanisms · Psychology · Gerontology · Internal Medicine

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