Association Between Frailty, 30-day Unplanned Readmission and Mortality After Hospitalization for Heart Failure

Results From the Nationwide Readmissions Database

Bibliographic Data

ID12798983
AuthorsMuni Rubens (0000-0003-1812-9753, Office of Clinical Research, Baptist Health South Florida, Miami, USA, corresponding author), Venkataraghavan Ramamoorthy (0000-0002-2448-6733, Baptist Health South Florida), Anshul Saxena (0000-0002-5573-2802, Florida International University), Juan Gabriel Ruíz (0000-0003-3088-5834, Florida International University), Juan G Ruiz-Pelaez (Florida International University), Md Ashfaq Ahmed (Baptist Health South Florida), Zhenwei Zhang (0000-0002-6762-9853, Baptist Health South Florida), Peter McGranaghan (0000-0002-5069-6638, Office of Clinical Research, Baptist Health South Florida, Miami, USA), Sandra Chaparro (0000-0003-2472-2641, Florida International University), Javier Jiménez (0000-0002-0402-4427, Florida International University), Javier León Jiménez (0000-0002-6059-4002, Baptist Health South Florida)
Year2023
Volume35
Issue9
Pages651-659
Publication date2023-01-19
Open AccessYes
TypeARTICLE
VenueJournal of Aging and Health (JOURNAL)
Journal identifiersISSN: 1552-6887 • E-ISSN: 0898-2643
PublisherSAGE Publishing (PUBLISHER • US)
DOI10.1177/08982643231152694
PMID36655743
OpenAlexW4317478291
LanguageEN
References cited16

Objectives: This study examined how frailty in traditional risk-adjusted models could improve the predictability of unplanned 30-day readmission and mortality among heart failure patients. Methods: This study was a retrospective analysis of Nationwide Readmissions Database data collected during the years 2010-2018. All patients ≥65 years who had a principal diagnosis of heart failure were included in the analysis. The Johns Hopkins Adjusted Clinical Groups frailty-defining diagnosis indicator was used to identify frail patients. Results: There was a total of 819,854 patients admitted for heart failure during the study period. Among them, 63,302 (7.7%) were frail. In the regression analysis, the risk of all-cause 30-day readmission (OR, 1.18; 95% CI, 1.14-1.22) and in-hospital mortality (OR, 1.52; 95% CI, 1.40-1.66) were higher in patients with frailty. Discussion: Inclusion of frailty in comorbidity-based risk-prediction models significantly improved the predictability of unplanned 30-day readmission and in-hospital mortality

Comorbidity · Database · Heart failure · Hospital readmission · Retrospective cohort study · Frailty in Older Adults · Heart Failure Treatment and Management · Medicine · Nutrition and Health in Aging · Emergency Medicine · Internal Medicine

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