Topography of Human Subjects Research Ethics in Uzbekistan
Analysis Using the Emanuel Benchmarks
Bibliographic Data
| ID | 12807540 |
|---|---|
| Authors | Dilfuza Aniyozova (0000-0002-7356-1736, Tashkent Institute Of Postgraduate Medical Education, corresponding author), Kerim Munir (0000-0002-2404-1806, Boston Children's Hospital) |
| Year | 2025 |
| Volume | 20 |
| Issue | 5 |
| Pages | 263-274 |
| Publication date | 2025-10-06 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Journal of Empirical Research on Human Research Ethics (JOURNAL) |
| Journal identifiers | ISSN: 1556-2646 • E-ISSN: 1556-2654 |
| Publisher | SAGE Publishing (PUBLISHER • US) |
| DOI | 10.1177/15562646251383010 |
| PMID | 41052008 |
| OpenAlex | W4414872250 |
| Language | EN |
| References cited | 12 |
Emanuel et al. (2004) proposed eight ethical benchmarks to assess the ethical integrity of human participants' research in low- and middle-income countries: collaborative partnership, social value, scientific validity, fair participant selection, favorable risk-benefit ratio, independent review, informed consent, and respect for recruited participants and their communities. We conducted a retrospective, descriptive analysis of 67 doctoral research proposals submitted between 2016 and 2019 to the Tashkent Institute of Postgraduate Medical Education in Uzbekistan.ResultsWhile all protocols addressed social value (67/67) and most demonstrated scientific validity (53/67) and collaborative partnership (40/67), far fewer adequately addressed fair participant selection (12/67), favorable risk-benefit ratio (3/67), independent review (3/67), informed consent (4/67), or respect for communities (3/67).ConclusionThis is the first empirical study to apply the Emanuel framework to doctoral research in Uzbekistan. The findings underscore the need for more systematic integration of these benchmarks into national ethics oversight and academic review procedures
Bioethics · Empirical research · Ethics committee · General partnership · Human research · Informed consent · Research design · Research ethics · Social research · Biomedical Ethics and Regulation · Ethics in Clinical Research · Ethics in medical practice
What Makes Clinical Research Ethical?
What Makes Clinical Research in Developing Countries Ethical? The Benchmarks of Ethical Research
International Ethical Guidelines for Health-related Research involving Humans
Ethical human participant research in Central Asia
What Makes Health Systems Research in Developing Countries Ethical? Application of the E manuel Framework for Clinical Research to H ealth S ystems Research
Using the Emanuel et al. Framework to Assess Ethical Issues Raised by a Biomedical Research Ethics Committee in South Africa
Research Ethics Committees’ Oversight of Biomedical Research in South Africa
| Citation velocity | historical |
|---|---|
| Highly cited | No |