Ethics and Genomic Editing Using the Crispr-Cas9 Technique
Challenges and Conflicts
Bibliographic Data
| ID | 12954201 |
|---|---|
| Authors | David Lorenzo (0000-0003-2042-0961, Universitat Ramon Llull, corresponding author), Montse Esquerda (0000-0002-5781-8298, Universitat de Lleida), Francesc Palau (0000-0002-8635-5421, Hospital Sant Joan de Déu Barcelona), Francisco José Cambra Lasaosa (0000-0002-3818-8032, Universitat Ramon Llull), Grup Investigació en Bioética (Universitat de Lleida) |
| Year | 2022 |
| Volume | 16 |
| Issue | 3 |
| Pages | 313-321 |
| Publication date | 2022-11-12 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | NanoEthics (JOURNAL) |
| Journal identifiers | ISSN: 1871-4757 • E-ISSN: 1871-4765 |
| Publisher | Springer Science+Business Media (PUBLISHER • DE) |
| DOI | 10.1007/s11569-022-00425-y |
| OpenAlex | W4309080781 |
| Language | EN |
| Citations received | 2 |
| References cited | 28 |
The field of genetics has seen major advances in recent decades, particularly in research, prevention and diagnosis. One of the most recent developments, the genomic editing technique Clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9, has opened the possibility for genetic therapies through genome modification. The technique marks an improvement on previous procedures but poses some serious ethical conflicts. Bioethics is the discipline geared at finding answers to ethical challenges posed by progress in medicine and biology and examining their repercussions for society. It can also offer a conceptualization of these ethical dilemmas. The aim of this paper is to offer a map of the ethical dilemmas associated with this technique by way of a critical analysis of current literature. The main issues can be grouped in four areas: efficacy and security; the types of cells which can be targeted by the technique (somatic, embryonic and gametes); the goal of the therapy; and accessibility and justice
Bioethics · Biology · Cas9 · Computational biology · Conceptualization · CRISPR · Economic Justice · Engineering ethics · Epistemology · Ethical issues · Genome editing · Philosophy of science · Political science · Biomedical Ethics and Regulation · Computer Science · CRISPR and Genetic Engineering · Engineering · Law · Philosophy · Pluripotent Stem Cells Research · Artificial Intelligence · Genetics
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Justice in CRISPR/Cas9 Research and Clinical Applications
Is Editing the Genome for Climate Change Adaptation Ethically Justifiable
CRISPR/Cas9 genome editing – new and old ethical issues arising from a revolutionary technology
| Citations per year | 2 |
|---|---|
| Citation span | 2026 - 2026 (1) |
| Highly cited | No |