Early Holocene preservation differences between cortical and trabecular bone proteomes
Bibliographic Data
| ID | 13095187 |
|---|---|
| Authors | Ragnheiður Diljá Ásmundsdóttir (0000-0002-8393-2326, University of Copenhagen), Jakob Lerche Hansen (0000-0001-5795-1761, Universitat Autonòma de Barcelona), Zandra Fagernäs (0000-0003-2667-3556, University of Copenhagen), Gaudry Troché (0000-0002-0404-4030, University of Copenhagen), Jesper V Olsen (0000-0002-4747-4938, University of Copenhagen), Maria Saña (0000-0002-8344-0639, Universitat Autonòma de Barcelona), Frido Welker (0000-0002-4846-6104, University of Copenhagen, corresponding author) |
| Year | 2024 |
| Volume | 57 |
| Pages | 104643-104643 |
| Publication date | 2024-06-25 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Journal of Archaeological Science Reports (JOURNAL) |
| Journal identifiers | ISSN: 2352-409X • E-ISSN: 2352-4103 |
| Publisher | Elsevier BV (PUBLISHER) |
| DOI | 10.1016/j.jasrep.2024.104643 |
| OpenAlex | W4399993979 |
| Language | EN |
| Citations received | 1 |
| References cited | 62 |
Skeletal sample selection for evolutionary palaeoproteomic studies is currently based on the availability of material, without taking into account the influence of bone biology on the proteome composition of living bone. A prime example concerns the cortical and trabecular bone that is present simultaneously in many skeletal elements, including those recovered from archaeological sites. These two bone components are formed and maintained in different manners and at different rates. In palaeoproteomics there is currently no empirical data demonstrating differences in composition and/or preservation of cortical and trabecular bone proteomes. Here we analyse pairs of cortical and trabecular bone from six Early Holocene ungulate rib specimens from the site of La Draga, Spain, using shotgun proteomics. We observe generally larger proteomes, a larger number of peptides, and lower rates of degradation, for the cortical bone samples compared to the trabecular bone samples. These results suggest that in degraded proteomic contexts, preference should be given to the sampling of cortical bone in order to maximise the retrieval of larger and better-preserved bone proteomes
Bioinformatics · Biology · Cortical bone · Osteoporosis · Proteome · Trabecular bone · Ungulate · Forensic and Genetic Research · Forensic Anthropology and Bioarchaeology Studies · Pleistocene-Era Hominins and Archaeology · Anatomy · Ecology · Endocrinology
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| Unique citing works | 1 |
|---|---|
| Citations per year | 1 |
| Citation span | 2025 - 2025 (1) |
| Citation velocity | recent |
| Highly cited | No |
| Citation types | Neutral: 1 |