Risk of Suicide Among Patients With Major Physical Disorders Considering Comorbidities of Mental Disorders
An Instrumental Variable Analysis
Bibliographic Data
| ID | 13629212 |
|---|---|
| Authors | Ning Lu (0000-0002-8110-9176, Governors State University, Illinois, IL, USA), Tzu-Jung Wen (Taipei Medical University, Taipei, Taiwan), Kuo-Cherh Huang (0000-0002-5222-7325, Taipei Medical University, Taipei, Taiwan, corresponding author) |
| Year | 2025 |
| Pages | 302228241312744-302228241312744 |
| Publication date | 2025-01-04 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | OMEGA - Journal of Death and Dying (JOURNAL) |
| Journal identifiers | ISSN: 0030-2228 • E-ISSN: 1541-3764 |
| Publisher | SAGE Publishing (PUBLISHER • US) |
| DOI | 10.1177/00302228241312744 |
| PMID | 39754563 |
| OpenAlex | W4406066265 |
| Language | EN |
| References cited | 43 |
Suicide is an important health concern. Excepting cancer, the association between physical disorders and suicidal risk is comparatively less explored. Instrumental variable analysis has been suggested as a powerful technique to deal with possible bias caused by unmeasured confounders in observational research. This population-based study set out to assess the suicidal risk of patients with major physical disorders by employing the instrumental variable analysis. Data were retrieved from the National Health Insurance Research Database and the Death Certification Registry in Taiwan (years 2010-2018). The Cox proportional hazards model with an instrumental variable estimator was performed, adjusting for comorbidities of mental disorders and other covariates. Analytical results showed that compared to their counterparts, patients with major physical disorders had an elevated risk of death by suicide within one year and three years after diagnosis of physical illness. Only did epilepsy not demonstrate a statistically significant impact on the risk of suicide
Comorbidity · Confounding · Environmental health · Instrumental variable · Mental health · Observational study · Population · Proportional hazards model · Psychiatry · Statistics · Advanced Causal Inference Techniques · Health disparities and outcomes · Internal Medicine · Medicine · Suicide and Self-Harm Studies
Suicide
Epidemiology of multimorbidity and implications for health care, research, and medical education
Propensity score methods for bias reduction in the comparison of a treatment to a non-randomized control group
Chronic Physical Conditions and Their Association With First Onset of Suicidal Behavior in the World Mental Health Surveys
An Introduction to Propensity Score Methods for Reducing the Effects of Confounding in Observational Studies
Disability in Daily Living Activities, Family Dysfunction, and Late-Life Suicide in Rural China
Population-Attributable Fractions of Axis I and Axis II Mental Disorders for Suicide Attempts
Physical illness, functional limitations, and suicide risk
Roles of physical and mental health in suicidal ideation in Canadian Armed Forces Regular Force veterans
Suicide attempts in the United States
| Highly cited | No |
|---|