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Physiological Reactions Induced by Grief

Bibliographic Data

ID13630572
AuthorsJerome F Fredrick (Research Laboratories, the Dodge Chemical Company of Boston, New York, Research Laboratories, Bronx, N.Y., corresponding author)
Year1971
Volume2
Issue2
Pages71-75
Publication date1971-07-01
Open AccessYes
TypeARTICLE
VenueOMEGA - Journal of Death and Dying (JOURNAL)
Journal identifiersISSN: 0030-2228 • E-ISSN: 1541-3764
PublisherSAGE Publishing (PUBLISHER • US)
DOI10.2190/gy55-0gya-cja4-64t4
OpenAlexW2038175717
LanguageEN
Citations received3
References cited22

The increase in mortality reported in individuals undergoing the stress imposed by the grief situation, may be directly traced to the overstimulation of the pituitary resulting in the production of excess quantities of adrenocorticotropic hormone (ACTH), which in turn causes increased levels of corticosteroids to be produced by the adrenal cortex. The physiologic affects of these substances include the suppression of the inflammatory response. Since the inflammatory response is essential to the immune mechanism of the individual, the bereaved becomes more susceptible to common bacterial, fungal and viral pathogens. Indeed, because of the suppression of this response, the grief-stricken person may fall prey to overwhelming infections which are caused by “opportunistic” micro-organisms. It seems possible that the stress imposed by grief may be at the basis for the increase in death rates of individuals who are bereaved

Adrenocorticotropic hormone · Grief · Hormone · Immune system · Inflammation · Inflammatory response · Psychotherapist · Stimulation · Grief, Bereavement, and Mental Health · Homelessness and Social Issues · Immunology · Internal Medicine · Medicine · Migration, Health and Trauma · Neuroscience · Psychology

  • Grief as a Disease Process

    Open Access•Jerome F Fredrick•OMEGA - Journal of Death and Dying•1977

  • Psychosocial Predictors of Death Prognosis

    Open Access•E Mansell Pattison, Ε Mansell Pattison•OMEGA - Journal of Death and Dying•1974

  • The Biochemistry of Bereavement

    Open Access•Jerome F Fredrick•OMEGA - Journal of Death and Dying•1983

  • Mortality of bereavement.

    Open Access•William D Rees, S G Lutkins•BMJ•1967

Citations per year0.06
Citation span1974 - 1983 (10)
Highly citedNo

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