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Rebound from D -Amphetamine

Bibliographic Data

ID13650321
AuthorsPaul M Hurst (Institute For Research, corresponding author), Sallyann K Bagley (Institute For Research), Nicholas C Chubb (Pennsylvania State University), Sherman Ross (Howard University)
Year1971
Volume29
Issue3_suppl
Pages1023-1033
Publication date1971-12-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenuePsychological Reports (JOURNAL)
Journal identifiersISSN: 0033-2941 • E-ISSN: 1558-691X
PublisherSAGE Publishing (PUBLISHER • US)
DOI10.2466/pr0.1971.29.3f.1023
PMID5139336
OpenAlexW2051227731
LanguageEN
Citations received1
References cited9

This experiment involves measurement of direct and delayed effects on mood and performance of single doses of d-amphetamine sulfate. The purpose was to determine whether or not the drug's initial positive effect on some aspects of behavior is followed by a reversal or “rebound” below the placebo baseline even when sleep deprivation is controlled. 43 university students, recruited as paid volunteers, were given 10 mg/77 kg, 15 mg/77 kg, and a placebo (lactose) on three separate occasions in counterbalanced order under double-blind conditions. Behavioral measures and mood self-ratings were obtained on the day of drug ingestion and at intervals on the following day. Measures were selected from those previously established as sensitive to the initial, direct effects of amphetamine. Although strong initial effects were obtained on some of the measures used, subsequent rebound was either slight or nonexistent. Implications and limitations are discussed

Amphetamine · Dopamine · Dose · Ingestion · Mood · Placebo · Cannabis and Cannabinoid Research · Clinical Psychology · Internal Medicine · Medicine · Neurotransmitter Receptor Influence on Behavior · Psychology · Substance Abuse Treatment and Outcomes

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  • Some Dimensions of Affective Response to Drugs

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Unique citing works1
Citations per year0,02
Citation span1972 - 1972 (1)
Citation velocityhistorical
Highly citedNo
Citation typesNeutral: 1

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