Efficacy of Lithium Chloride in the Taste-Aversion Conditioning of Young-Adult and Old-Age Rats

Bibliographic Data

ID13653248
AuthorsJames R Misanin (Susquehanna University, corresponding author), Charles F Hinderliter (University of Pittsburgh at Johnstown)
Year1994
Volume75
Issue1
Pages267-271
Publication date1994-08-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenuePsychological Reports (JOURNAL)
Journal identifiersISSN: 0033-2941 • E-ISSN: 1558-691X
PublisherSAGE Publishing (PUBLISHER • US)
DOI10.2466/pr0.1994.75.1.267
PMID7984736
OpenAlexW2006057883
LanguageEN
Citations received2
References cited7

An absolute amount of a LiCl US was administered to 24 young-adult and 24 old-age rats during taste-aversion conditioning to determine whether the superior performance of old-age rats, when a 1% body-weight injection of a LiCl US is administered 3 hr. after a saccharin CS, is due to age-related differences in US intensity or the efficacy of LiCl. The aversion conditioned in old-age rats with a 3-hr. CS-US interval and an absolute amount of LiCl was still significantly greater than that in young adults suggesting that age-related differences in US intensity or the efficacy of LiCl cannot explain the superior performance of old-age rats. Possibly, old-age rats forget the specifics of the CS more than young adults and, thus, older animals show greater stimulus generalization to the substantially different test stimuli

Age groups · Body weight · Classical conditioning · Conditioning · Developmental psychology · Lithium chloride · Saccharin · Stimulus (psychology · Taste · Taste aversion · Young adult · Chemistry · Demography · Endocrinology · Internal Medicine · Medicine · Memory and Neural Mechanisms · Neuroscience · Neuroscience and Neuropharmacology Research · Psychology · Receptor Mechanisms and Signaling

Tools

Open DOISci-Hub