Prednisolone Blocks Extreme Intermale Social Aggression in Seizure-Induced, Brain-Damaged Rats
Implications for the Amygdaloid Central Nucleus, Corticotrophin-Releasing Factor, and Electrical Seizures
Bibliographic Data
| ID | 13666996 |
|---|---|
| Authors | Alexandra Bédard (0000-0002-0526-6022, Laurentian University, corresponding author), A W Bedard (Laurentian University), Michael A Persinger (Laurentian University) |
| Year | 1995 |
| Volume | 77 |
| Issue | 1 |
| Pages | 3-9 |
| Publication date | 1995-08-01 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Psychological Reports (JOURNAL) |
| Journal identifiers | ISSN: 0033-2941 • E-ISSN: 1558-691X |
| Publisher | SAGE Publishing (PUBLISHER • US) |
| DOI | 10.2466/pr0.1995.77.1.3 |
| PMID | 7501771 |
| OpenAlex | W2009764725 |
| Language | EN |
| Citations received | 1 |
| References cited | 11 |
In two separate blocks of experiments, the extreme within-group aggression which is typically associated with limbic seizure-induced brain injury in male rats was attenuated or abolished within two days by the administration of prednisolone in the water supply. The effect was specific to the aggression and was not simulated by dexamethasone. The results support the hypothesis that interference with inhibitory inputs to the central nucleus of the amygdala and the enhanced stimulation by corticotrophin-releasing factor facilitates physical aggression within groups of male rats. Potential relevance to curbing aggression ("conflict") between groups of male humans is discussed
Aggression · Agonistic behaviour · Amygdala · Developmental psychology · Dexamethasone · Nucleus · Prednisolone · Stimulation · Stria terminalis · Endocrinology · Internal Medicine · Medicine · Neuroendocrine regulation and behavior · Neuroscience · Neuroscience and Neuropharmacology Research · Psychology · Stress Responses and Cortisol
| Citations per year | 0.02 |
|---|---|
| Citation span | 1980 - 1980 (1) |
| Highly cited | No |