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Heroin Addiction is Associated With Cognitive Deficiency, Neurobiological Alterations and Socio-Demographic Factors in Adolescents

Bibliographic Data

ID13669348
AuthorsZunera Tanveer (0000-0002-9250-0103, University of Lahore), Muhammad Rafiq (0000-0002-1602-4782, University of Lahore), Irfan Shahzad Sheikh (0000-0003-0616-0411, University of Balochistan), Hafiz Muhammad Ali (0000-0002-9885-5933, Islamia University of Bahawalpur, corresponding author), Mohammad Zahid Mustafa (0000-0003-0899-6503, University of Balochistan, corresponding author), Tehmina Maqbool (0009-0005-8593-3671, University of Lahore), Saima Asif (Bahauddin Zakariya University), Bader O Almutairi (0000-0002-4697-5204, King Saud University), Kun Luo (0000-0002-5754-0222, Shenzhen Technology University), Kaixin Luo (Shenzhen Technology University)
Year2025
Pages332941251400691-332941251400691
Publication date2025-11-29
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenuePsychological Reports (JOURNAL)
Journal identifiersISSN: 0033-2941 • E-ISSN: 1558-691X
PublisherSAGE Publishing (PUBLISHER • US)
DOI10.1177/00332941251400691
PMID41316925
OpenAlexW4416814604
LanguageEN
References cited38

The development and growth of cognitive traits at adolescence is a multidimensional progression and drug addiction at this stage imparts significant detrimental effects on cognitive behavior and executive ability of brain. In this cross-sectional study, the adolescents with heroin use disorder with (G2) or without (G3) treatment were compared with the healthy controls (G1). Their socio-demographic data were collected, cognition was assessed by Stroop color word and colored number tests. Serum BDNF and dopamine analysis was done by ELISA. Time Interference Score was found to be significantly ( p p p p p p p p p p < 0.001) strong relationship that more the time spent by the person in the rehabilitation center, the less was the rate of relapse of the problem. It has therefore been concluded that socio-demographic factors play a crucial role in heroin addiction that ultimately severely affects their neurological development and thus, impairs the behavioral and learning abilities. However, a proper rehabilitation therapy could restore their social and mental health

Addiction · Cognition · Cognitive skill · Dopamine · Heroin · Socioeconomic status · Stroop effect · Substance abuse · Neurotransmitter Receptor Influence on Behavior · Prenatal Substance Exposure Effects · Substance Abuse Treatment and Outcomes

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Highly citedNo

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