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Emotionality and the Course of Collagen Arthritis in the Rat

Bibliographic Data

ID13670562
AuthorsDavid P Nowlis (Sir Mortimer B. Davis—Jewish General Hospital, Montréal, corresponding author)
Year1984
Volume55
Issue3
Pages875-882
Publication date1984-12-01
Open AccessYes
TypeARTICLE
VenuePsychological Reports (JOURNAL)
Journal identifiersISSN: 0033-2941 • E-ISSN: 1558-691X
PublisherSAGE Publishing (PUBLISHER • US)
DOI10.2466/pr0.1984.55.3.875
PMID6522553
OpenAlexW2039938225
LanguageEN
Citations received2
References cited22

43 female Sprague-Dawley rats were tested for emotionality using standard open-field procedures. The subjects were then injected with emulsified collagen-II. 31 responded with arthritic activity, clearly evidencing edema and erythema in from one to all 4 limbs. Duration of active response varied from 29 to 59 days. For the arthritic rats, severity of disease (combining duration and number of limbs by standard scores) correlated with both premorbid emotionality (where the partial r, controlling for preweight, was .47, with p < .01), and premorbid weight (where the partial r, controlling for pre-emotionality, was .38, with p < .05). The results encourage further study of premorbid behavioral tendencies as predictors of variations in arthritic responsivity

Arthritis · Developmental psychology · Emotionality · Erythema · Open field · Psychiatry · Adipokines, Inflammation, and Metabolic Diseases · Immune Cell Function and Interaction · Immunology · Internal Medicine · Medicine · Psychology · Regulation of Appetite and Obesity

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Citations per year0.06
Citation span1993 - 1993 (1)
Highly citedNo

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