Extreme Hypothermia Induced by a Synergism of Acute Limbic Seizures, Physical Restraint, and Acepromazine
Implications for Survival following Brain Injury
Bibliographic Data
| ID | 13673783 |
|---|---|
| Authors | Y Bureau (0000-0001-7995-8892, Laurentian University, corresponding author), Y R J Bureau (Laurentian University), Michael A Persinger (Laurentian University) |
| Year | 1993 |
| Volume | 72 |
| Issue | 1 |
| Pages | 248-250 |
| Publication date | 1993-02-01 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Psychological Reports (JOURNAL) |
| Journal identifiers | ISSN: 0033-2941 • E-ISSN: 1558-691X |
| Publisher | SAGE Publishing (PUBLISHER • US) |
| DOI | 10.2466/pr0.1993.72.1.248 |
| PMID | 8383859 |
| OpenAlex | W2008208506 |
| Language | EN |
| Citations received | 1 |
| References cited | 5 |
Core temperature was measured in rats 24 hr. after they had been assigned to one of 8 groups in a 3-way analysis of variance design that involved (1) induction of limbic seizures by a systemic injection of lithium/pilocarpine, (2) physical restraint, and (3) administration of acepromazine. An extraordinarily powerful interaction was noted among seizures, physical restraint, and acepromazine-produced hypothermia (24 degrees C) compared to the other 7 treatments (> 35 degrees C). The putative poikilothermic response is commensurate with the loss of mammalian behaviors that follow these seizures. Implications for survival during the acute stages of brain injury are suggested
Acepromazine · Anesthesia · Epilepsy · Heart rate · Hypothermia · Pilocarpine · Cardiac Arrest and Resuscitation · Climate Change and Health Impacts · Internal Medicine · Medicine · Neuroscience · Psychology · Thermal Regulation in Medicine
| Citations per year | 0.03 |
|---|---|
| Citation span | 1994 - 1994 (1) |
| Highly cited | No |