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Effect of Bilateral Spreading Depression and Scopolamine on Motor Activity in Rats

Bibliographic Data

ID13675584
AuthorsBarton Meyers (Brooklyn College of the City University of New York, corresponding author), Warren C Stern (Brooklyn College of the City University of New York)
Year1966
Volume18
Issue1
Pages267-270
Publication date1966-02-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenuePsychological Reports (JOURNAL)
Journal identifiersISSN: 0033-2941 • E-ISSN: 1558-691X
PublisherSAGE Publishing (PUBLISHER • US)
DOI10.2466/pr0.1966.18.1.267
PMID5908492
OpenAlexW2026160260
LanguageEN
References cited11

Rats ( N = 40) were surgically prepared to receive bilateral cortical spreading depression. Approximately 24 hr. postoperatively their level of motor activity was measured after administration of scopolamine or saline in the presence or absence of spreading depression (2 × 2 design). Although the data seemed to reflect a slight activating effect of scopolamine, they clearly indicated a significant depressant effect of spreading depression on motor activity which suggests that spreading depression may impair learning tasks by reducing motor activity

Anesthesia · Cortical spreading depression · Depression (economics · Motor activity · Psychiatry · Saline · Scopolamine · Internal Medicine · Medicine · Memory and Neural Mechanisms · Neuroscience and Neuropharmacology Research · Psychology · Stress Responses and Cortisol

Citation velocityhistorical
Highly citedNo

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